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Table 3 Diagnostic performances of three methods (tPSA, NLR and tPSA + NLR)

From: The values of neutrophil-lymphocyte ratio and/or prostate-specific antigen in discriminating real Gleason score ≥ 7 prostate cancer from group of biopsy-based Gleason score ≤ 6

 

tPSA

NLR

P value

tPSA + NLR

tPSA

P value

tPSA + NLR

NLR

P value

Sensitivity

60/100(60.0%)

42/100(42.0%)

0.006

71/100(71.0%)

60/100(60.0%)

0.001

71/100(71.0%)

42/100(42.0%)

<0.001

Specificity

49/61(80.3%)

51/61(88.5%)

0.227

46/61(75.4%)

49/61(80.3%)

0.250

46/61(75.4%)

51/61(88.5%)

0.008

PPV

60/72(83.3%)

42/49(85.7%)

 

71/86(82.6%)

60/72(83.3%)

 

71/86(82.6%)

42/49(85.7%)

 

NPV

49/89(55.1%)

54/112(48.2%)

 

46/75(61.3%)

49/89(55.1%)

 

46/75(61.3%)

54/112(48.2%)

 

Accuracy

109/161(67.7%)

93/161(59.6%)

0.132

117/161(72.7%)

109/161(67.7%)

0.330

117/161(72.7%)

93/161(59.6%)

0.013

  1. PPV Positive predictive value, NPV Negative predictive value