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Table 2 Tumor burden and Oncotype DX recurrence score

From: The association between smoking and breast cancer characteristics and outcome

Population (num) Tumor size Macroscopic node positivea Stage (%) Oncotype Dx RS
Mean cm (SD) P (%) P I II III P Mean (SD) P
All (662) 1.67 (0.78) _ 8.8 _ 71.3 28.4 0.3 _ 19.03 (10.23) _
Hx smokingb
 Yes (173) 1.66 (0.87) 0.642 9.9 0.574 73.8 25.6 0.6 0.695 18.69 (9.15) 0.447
 No (439) 1.69 (0.75) 8.5 69.4 30.4 0.2 19.35 (10.78)
Current smokingb
 Yes (101) 1.76 (0.98) 0.392 8 0.73 73.0 26.0 1.0 0.613 19.42 (8.52) 0.70
 No (508) 1.67 (0.74) 9.1 70.2 29.6 0.2 19.05 (10.49)
Number of pack years (PY)
 PY2 0–29 (518) 1.68 (0.76) 0.82 9.5 0.38 69 30.6 0.4 0.172 19.25 (10.66) 0.454
 PY > =30 (66) 1.65 (0.96) 6.2 80.0 20.0 0 18.37 (8.68)
  1. aMacroscopic nodes- lymph node metastases >2 mm
  2. bData regarding smoking was retrieved during the first visit at the oncologist clinic. Current smokers were defined as patients who actively smoked at the time of breast cancer diagnosis. Patients with history of smoking were defined as ever smoker
  3. - Abbreviations: cm centimeter, Hx history, PY pack years, RS recurrence score, SD standard deviation
  4. - Data were not available for: Hx smoking (n = 49); nodal status (n = 2); PY (n = 77); smoking status (n = 52); Stage (n = 2); Tumor size (n = 1)
  5. - Cohort included patients with ER positive, HER2 negative disease