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Table 1 Incident cases of lung cancer, Estonia 1985–2014

From: Divergent trends in lung cancer incidence by gender, age and histological type in Estonia: a nationwide population-based study

  Period of diagnosis p-valuea
1985–89 1990–94 1995–99 2000–04 2005–09 2010–14
Men
 Total number of cases 2912 3232 3200 3054 2975 3026  
 Microscopic verification (%) 70.8 72.5 73.6 74.1 72.3 76.6 p < 0.001
 Death certificate only (%) 0.2 1.2 1.6 4.5 4.3 3.8 p < 0.001
 Autopsy cases (%) 7.2 5.2 3.3 3.3 3.0 2.1 p < 0.001
Morphology (%)b
 Small cell carcinoma 24.2 23.7 20.8 21.3 19.6 16.4 p < 0.001
 Squamous cell carcinoma 39.0 45.3 49.7 49.1 46.4 42.0 p = 0.04
 Adenocarcinoma 9.7 8.0 10.0 12.1 15.7 23.0 p < 0.001
 Large cell carcinoma 6.2 6.3 7.3 9.5 11.0 11.1 p < 0.001
 Other specified 0.9 0.9 1.1 1.9 2.6 4.8 p < 0.001
 NOS 20.1 15.9 11.2 6.2 4.7 2.7 p < 0.001
Age at diagnosis (%)
 15–54 years 19.8 18.1 14.3 12.2 10.4 7.6 p < 0.001
 55–64 years 43.3 40.9 35.3 27.7 24.9 27.3 p < 0.001
 65–74 years 24.8 30.2 39.7 42.2 39.8 36.8 p < 0.001
 ≥75 years 12.1 10.8 10.8 17.9 24.9 28.3 p < 0.001
 Median age at diagnosis (years) 61 63 65 67 68 69  
Women
 Total number of cases 582 601 678 766 805 1059  
 Microscopic verification (%) 59.0 60.6 63.0 68.4 68.1 74.6 p < 0.001
 Death certificate only (%) 0.2 1.7 2.2 4.3 4.6 3.5 p < 0.001
 Autopsy cases (%) 10.1 7.8 3.4 3.9 2.0 2.1 p < 0.001
Morphology (%)b
 Small cell carcinoma 26.2 27.5 24.8 21.6 19.3 13.5 p < 0.001
 Squamous cell carcinoma 22.5 21.7 25.3 28.1 22.8 22.0 p = 0.87
 Adenocarcinoma 19.8 20.3 22.5 28.4 34.5 40.3 p < 0.001
 Large cell carcinoma 8.5 8.5 8.9 12.0 11.9 12.4 p = 0.05
 Other specified 1.8 1.7 4.7 4.0 5.1 9.9 p < 0.001
 NOS 21.3 20.3 13.8 5.9 6.4 1.9 p < 0.001
Age at diagnosis (%)
 15–54 years 12.9 11.3 11.4 12.3 9.8 8.4 p < 0.001
 55–64 years 32.5 25.0 17.7 21.0 22.5 21.6 p < 0.001
 65–74 years 33.0 39.9 43.8 32.6 30.1 33.2 p = 0.92
 ≥75 years 21.7 23.8 27.0 34.1 37.6 36.7 p < 0.001
 Median age at diagnosis (years) 65 68 69 71 70 71  
  1. aComparing proportions for the first and last period
  2. bAmong microscopically verified cases