Table 1 Incident cases of lung cancer, Estonia 1985–2014
Period of diagnosis | p-valuea | ||||||
|---|---|---|---|---|---|---|---|
1985–89 | 1990–94 | 1995–99 | 2000–04 | 2005–09 | 2010–14 | ||
Men | |||||||
Total number of cases | 2912 | 3232 | 3200 | 3054 | 2975 | 3026 | |
Microscopic verification (%) | 70.8 | 72.5 | 73.6 | 74.1 | 72.3 | 76.6 | p < 0.001 |
Death certificate only (%) | 0.2 | 1.2 | 1.6 | 4.5 | 4.3 | 3.8 | p < 0.001 |
Autopsy cases (%) | 7.2 | 5.2 | 3.3 | 3.3 | 3.0 | 2.1 | p < 0.001 |
Morphology (%)b | |||||||
Small cell carcinoma | 24.2 | 23.7 | 20.8 | 21.3 | 19.6 | 16.4 | p < 0.001 |
Squamous cell carcinoma | 39.0 | 45.3 | 49.7 | 49.1 | 46.4 | 42.0 | p = 0.04 |
Adenocarcinoma | 9.7 | 8.0 | 10.0 | 12.1 | 15.7 | 23.0 | p < 0.001 |
Large cell carcinoma | 6.2 | 6.3 | 7.3 | 9.5 | 11.0 | 11.1 | p < 0.001 |
Other specified | 0.9 | 0.9 | 1.1 | 1.9 | 2.6 | 4.8 | p < 0.001 |
NOS | 20.1 | 15.9 | 11.2 | 6.2 | 4.7 | 2.7 | p < 0.001 |
Age at diagnosis (%) | |||||||
15–54 years | 19.8 | 18.1 | 14.3 | 12.2 | 10.4 | 7.6 | p < 0.001 |
55–64 years | 43.3 | 40.9 | 35.3 | 27.7 | 24.9 | 27.3 | p < 0.001 |
65–74 years | 24.8 | 30.2 | 39.7 | 42.2 | 39.8 | 36.8 | p < 0.001 |
≥75 years | 12.1 | 10.8 | 10.8 | 17.9 | 24.9 | 28.3 | p < 0.001 |
Median age at diagnosis (years) | 61 | 63 | 65 | 67 | 68 | 69 | |
Women | |||||||
Total number of cases | 582 | 601 | 678 | 766 | 805 | 1059 | |
Microscopic verification (%) | 59.0 | 60.6 | 63.0 | 68.4 | 68.1 | 74.6 | p < 0.001 |
Death certificate only (%) | 0.2 | 1.7 | 2.2 | 4.3 | 4.6 | 3.5 | p < 0.001 |
Autopsy cases (%) | 10.1 | 7.8 | 3.4 | 3.9 | 2.0 | 2.1 | p < 0.001 |
Morphology (%)b | |||||||
Small cell carcinoma | 26.2 | 27.5 | 24.8 | 21.6 | 19.3 | 13.5 | p < 0.001 |
Squamous cell carcinoma | 22.5 | 21.7 | 25.3 | 28.1 | 22.8 | 22.0 | p = 0.87 |
Adenocarcinoma | 19.8 | 20.3 | 22.5 | 28.4 | 34.5 | 40.3 | p < 0.001 |
Large cell carcinoma | 8.5 | 8.5 | 8.9 | 12.0 | 11.9 | 12.4 | p = 0.05 |
Other specified | 1.8 | 1.7 | 4.7 | 4.0 | 5.1 | 9.9 | p < 0.001 |
NOS | 21.3 | 20.3 | 13.8 | 5.9 | 6.4 | 1.9 | p < 0.001 |
Age at diagnosis (%) | |||||||
15–54 years | 12.9 | 11.3 | 11.4 | 12.3 | 9.8 | 8.4 | p < 0.001 |
55–64 years | 32.5 | 25.0 | 17.7 | 21.0 | 22.5 | 21.6 | p < 0.001 |
65–74 years | 33.0 | 39.9 | 43.8 | 32.6 | 30.1 | 33.2 | p = 0.92 |
≥75 years | 21.7 | 23.8 | 27.0 | 34.1 | 37.6 | 36.7 | p < 0.001 |
Median age at diagnosis (years) | 65 | 68 | 69 | 71 | 70 | 71 | |