A survey of the clinicopathological and molecular characteristics of patients with suspected Lynch syndrome in Latin America

Table 9 Summary of family history analysis from published data from suspected Latin America LS families

Latin American Databases	Number of families	Number of individuals	Clinical criteria			Interpreted as Sporadic cases	Suspected LS (%)	Non-suspected LS (%)	Median age at CRC diagnosis
Latin American Databases	Number of families	Number of individuals	AMSII	Revised Bethesda	Other criteria	Interpreted as Sporadic cases	Suspected LS (%)	Non-suspected LS (%)	Median age at CRC diagnosis
Mexico City, Mexico [49]	210	210	2	0	56	154	2 (0.95)	208 (99.05)	na
Asuncion, Paraguay [50]	324	324	9	0	na	315	9 (2.8)	315 (97.2)	55
Sao Paulo, Brazil [19]	311	311	4	41	213	98	45 (31.5)	266 (85.5)	na
Lima, Peru [33]	86	86	20	31	80	6	51 (59.3)	35 (40.7)	na
Total	931	931	35	72	349	573	107 (11.5)	824 (88.6)

na not applied, MMR mismatch-repair genes, CRC colorectal cancer, LS Lynch syndrome

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