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Table 9 Summary of family history analysis from published data from suspected Latin America LS families

From: A survey of the clinicopathological and molecular characteristics of patients with suspected Lynch syndrome in Latin America

Latin American Databases Number of families Number of individuals Clinical criteria Interpreted as Sporadic cases Suspected LS (%) Non-suspected LS (%) Median age at CRC diagnosis
AMSII Revised Bethesda Other criteria
Mexico City, Mexico [49] 210 210 2 0 56 154 2 (0.95) 208 (99.05) na
Asuncion, Paraguay [50] 324 324 9 0 na 315 9 (2.8) 315 (97.2) 55
Sao Paulo, Brazil [19] 311 311 4 41 213 98 45 (31.5) 266 (85.5) na
Lima, Peru [33] 86 86 20 31 80 6 51 (59.3) 35 (40.7) na
Total 931 931 35 72 349 573 107 (11.5) 824 (88.6)  
  1. na not applied, MMR mismatch-repair genes, CRC colorectal cancer, LS Lynch syndrome
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