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Table 7 Comparison of MMR- deficient versus MMR- proficient individuals from suspected Latin America LS families

From: A survey of the clinicopathological and molecular characteristics of patients with suspected Lynch syndrome in Latin America

Clinical characteristics MMR status p value
Deficient Proficient
Age at CRC diagnosis (mean + − SD) 42.47 36.3  
Gender (n(%))
 Male 27 (39.1) 36 (34.6)  
 Female 42 (60.9) 68 (65.4) 0.545637
Family history of CRC (n(%))
 Yes 66 (98.5) 40 (87)  
 No 1 (1.5) 6 (13) 0.012333
Family history Lynch syndrome associated cancers (n(%))
 Yes 14 (20.9) 6 (13)  
 No 53 (79.1) 40 (87) 0.282626
AMSII/Bethesda criteria (n(%))
 AMSII 28 (42.4) 5 (10.9)  
 Bethesda 38 (57.6) 41 (89.1) 0.000314
  1. *P ≤ 0.05; CRC colorectal cancer, MMR mismatch repair
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