Identification of predictive markers of the therapeutic effect of eribulin chemotherapy for locally advanced or metastatic breast cancer

Table 5 Univariate and multivariate analysis with respect to progression free survival in 22 triple-negative breast cancers

Parameters	Univarite analysis			Multivariate analysis
Parameters	Hazard ratio	95% CI	p value	Hazard ratio	95% CI	p value
Age at operation
≤ 63 vs >63	0.787	0.249–2.489	0.683
Degree of progress
Locally advanced vs Visceral metastases	0.509	0.136–1.909	0.317
Life threatening condition
non- Life threatening vs Life threatening	1.368	0.403–4.647	0.615
Nuclear grade
1, 2, vs 3	0.534	0.154–1.849	0.322
Ki67
Negative vs Positive	0.295	0.083–1.052	0.060	0.190	0.024–1.482	0.113
GSTP1
Negative vs Positive	1.514	0.402–5.709	0.540
β-tubulin class III
Negative vs Positive	0.548	0.147–2.046	0.371
TLE3
Negative vs Positive	0.148	0.028–0.788	0.025	0.126	0.018–0.885	0.037

GSTP 1 glutathione S-transferase pi 1, TLE3 transducin-like enhancer of split 3, CI confidence intervals

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