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Up-modulation of PLC-β2 reduces the number and malignancy of triple-negative breast tumor cells with a CD133+/EpCAM+ phenotype: a promising target for preventing progression of TNBC

  • Federica Brugnoli1,
  • Silvia Grassilli1,
  • Paola Lanuti2, 3,
  • Marco Marchisio2, 3,
  • Yasamin Al-Qassab1, 4,
  • Federica Vezzali1,
  • Silvano Capitani1, 5 and
  • Valeria Bertagnolo1Email author
BMC Cancer201717:617

https://doi.org/10.1186/s12885-017-3592-y

Received: 17 November 2016

Accepted: 22 August 2017

Published: 4 September 2017

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Open Peer Review reports

Pre-publication versions of this article and author comments to reviewers are available by contacting info@biomedcentral.com.

Original Submission
17 Nov 2016 Submitted Original manuscript
3 Mar 2017 Reviewed Reviewer Report - Samantha Oakes
23 Apr 2017 Reviewed Reviewer Report - Sushanta Banerjee
25 Jul 2017 Author responded Author comments - Federica Brugnoli
Resubmission - Version 2
25 Jul 2017 Submitted Manuscript version 2
25 Jul 2017 Reviewed Reviewer Report - Sushanta Banerjee
11 Aug 2017 Reviewed Reviewer Report - Samantha Oakes
21 Aug 2017 Author responded Author comments - Federica Brugnoli
Resubmission - Version 3
21 Aug 2017 Submitted Manuscript version 3
Publishing
22 Aug 2017 Editorially accepted
4 Sep 2017 Article published 10.1186/s12885-017-3592-y

How does Open Peer Review work?

Open peer review is a system where authors know who the reviewers are, and the reviewers know who the authors are. If the manuscript is accepted, the named reviewer reports are published alongside the article. Pre-publication versions of the article and author comments to reviewers are available by contacting info@biomedcentral.com. All previous versions of the manuscript and all author responses to the reviewers are also available.

You can find further information about the peer review system here.

Authors’ Affiliations

(1)
Signal Transduction Unit, Division of Anatomy and Histology, Department of Morphology, Surgery and Experimental Medicine, University of Ferrara
(2)
Department of Medicine and Aging Science, “G. d’Annunzio” University of Chieti-Pescara
(3)
Center of Aging Sciences and Translational Medicine (CeSI-MeT), “G. d’Annunzio” University of Chieti-Pescara
(4)
College of Medicine, Department of Anatomy, University of Baghdad
(5)
LTTA Centre, University of Ferrara

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