Table 4 Univariate and multivariate analysis for progression-free survival predictors in patients with glioma
From: Prognostic significance of E-cadherin and N-cadherin expression in Gliomas
Characteristics | No | Mean (months) | P-value (univariate) | P-value (multivariate) | Hazard ratio | |
|---|---|---|---|---|---|---|
Age | <60 | 63 | 47.0 | <0.001 | 0.002 | 1 |
≥60 | 29 | 13.4 | 2.673 | |||
Sex | M | 42 | 33.1 | 0.623 | 0.432 | 1 |
F | 50 | 38.1 | 0.775 | |||
WHO grade | Low (I-II) | 34 | 58.8 | <0.001 | <0.001 | 1 |
High (III-IV) | 58 | 22.7 | 5.278 | |||
Tumor size | <4.5 | 49 | 43.0 | 0.046 | 0.255 | 1 |
≥4.5 | 43 | 28.4 | 1.487 | |||
Location | Non-eloquent area | 45 | 42.3 | 0.549 | 0.913 | 1 |
Near eloquent area | 47 | 44.1 | 0.966 | |||
Edema | None/minimal | 42 | 41.4 | 0.800 | 0.794 | 1 |
Moderate/severe | 50 | 45.0 | 0.920 | |||
Cystic change | None | 40 | 45.8 | 0.840 | 0.954 | 1 |
Present | 52 | 42.1 | 1.019 | |||
Resection degree | Partial/subtotal | 34 | 42.8 | 0.746 | 0.473 | 1 |
Gross total | 58 | 44.4 | 1.248 | |||
E-cadherin | No | 28 | 46.5 | 0.654 | 0.838 | 1 |
Positive | 64 | 31.7 | 1.111 | |||
N-cadherin | Low | 68 | 38.2 | 0.058 | 0.463 | 1 |
High | 24 | 24.9 | 1.333 | |||