Table 1 Clinical characteristics of 88 critically ill cancer patients at the time of brain MRI for clinical suspicion of cerebral infarction in the ICU
From: D-dimer levels and cerebral infarction in critically ill cancer patients
Characteristics | No. of patients (%) or median (IQR) |
|---|---|
Age, years | 63 (53–69) |
Gender, male | 51 (58) |
Type of malignancy | |
Solid tumor | 33 (38) |
Hematologic | 55 (63) |
Vascular risk factors | |
Hypertension | 35 (40) |
Diabetes mellitus | 20 (23) |
Past and current smoking | 31 (35) |
Ischemic heart disease | 3 (3) |
Hypercholesterolemia | 5 (6) |
Atrial fibrillation | 19 (22) |
Alcohol abuse | 4 (5) |
Family history of stroke | 7 (8) |
Previous thrombotic event | 10 (11) |
Ischemic stroke | 3 (3) |
Myocardial infarction | 4 (5) |
Deep vein thrombosis | 2 (2) |
Pulmonary thromboembolism | 1 (1) |
Neurological deficits | |
Decreased mentality or delirium | 55 (63) |
Hemiparesis | 28 (32) |
Seizure | 20 (23) |
Abnormal movement | 6 (7) |
Anisocoric pupil or abnormal pupil reflex | 3 (3) |
Abnormal respiratory pattern | 2 (2) |
Other | 7 (8) |
Time interval from ICU admission to brain MRI, days | 4.4 (1.1–12.4) |
Recent chemotherapy | 44 (50) |
Anticoagulation use | 20 (23) |
Antiplatelet use | 3 (3) |
DIC | 3 (3) |
D-dimer levels (μg/mL) | 4.55 (2.66–11.15) |
Fibrinogen | 327 (195–477) |
CRP | 6.43 (3.29–15.95) |
Procalcitonin | 1.05 (0.27–3.77) |