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Table 5 Differences in LINE-1 methylation levels between cases and controls

From: LINE-1 hypermethylation in white blood cell DNA is associated with high-grade cervical intraepithelial neoplasia

LINE-1 methylation levels

Cases (n = 71)

Controls (n = 68)

p-value a

Median

IQR

Median

IQR

Site 1

70.00

21.00

66.00

17.00

0.103

Site 2

76.00

4.00

75.00

5.00

0.090

Site 3

78.00

3.00

77.00

5.00

0.032

Mean (all three sites)

75.00

6.00

73.17

2.92

0.002

  1. Abbreviations: LINE-1 Long Interspersed Nuclear Element- 1, IQR Interquartile range
  2. aStatistically significant p values (p < 0.05), based on the Mann-Whitney U test, are indicated in bold font