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Table 8 Multivariate analysis with Cox proportional hazard model

From: Propensity score matching analysis of a phase II study on simultaneous modulated accelerated radiation therapy using helical tomotherapy for nasopharyngeal carcinomas

Factor 3-year LRRFS 3-year DMFS 3-year DFS 3-year OS
HR (95% CI) P* HR (95% CI) P* HR (95% CI) P* HR (95% CI) P*
Treatment pattern (P67.5 vs.P70) 0.653 (0.249-1.714) 0.387 0.682 (0.286-1.623) 0.387 0.564 (0.310-1.024) 0.060 0.476 (0.236-0.957) 0.037
Gender (female vs. male) 2.481 (0.927-6.644) 0.071 0.279 (0.065-1.209) 0.088 0.878 (0.431-1.791) 0.721 0.765 (0.328-2.411) 0.535
Age (≥50 vs. <50 years) 2.672 (0.990-7.216) 0.052 2.617 (1.076-6.364) 0.034 3.058 (1.659-5.635) 0.000 2.914 (1.434-5.921) 0.003
T Stage (3–4 vs.1-2) 2.715 (0.784-9.404) 0.115 0.391 (0.105-1.453) 0.161 1.196 (0.558-2.562) 0.646 0.960 (0.382-2.411) 0.931
Node category (N+ vs. N-) 0.957 (0.172-5.328) 0.960 1.891 (0.389-9.196) 0.430 1.856 (0.607-5.681) 0.278 1.542 (0.483-4.925) 0.465
N Stage (2–3 vs. 0–1) 1.423 (0.383-5.291) 0.598 0.359 (0.085-1.515) 0.163 0.801 (0.351-1.824) 0.597 0.691 (0.255-1.872) 0.467
UICC Stage (III-IV vs. I-II) 4.031 (0.338-48.101) 0.270 9.786 (1.448-66.128) 0.019 4.487 (1.245-16.166) 0.022 4.208 (1.026-17.263) 0.046
  1. Abbreviations HR hazard ratio, CI confidence interval
  2. *P-values were calculated using the adjusted Cox proportional-hazards model