Table 2 Pre-diagnostic use of warfarin compared to anticoagulant non-users and warfarin usage in comparison with other anticoagulant drugs stratified by Defined Daily Doses (DDD), duration and intensity of usage
| Â | n of deaths | Age-adjusted | Multivariable-adjusted |
|---|---|---|---|
Warfarin compared to non-users | |||
 None | 624 | Ref | Ref |
 Any | 65 | 1.11 (0.85-1.44) | 1.15 (0.88-1.49) |
Amount of warfarin use | |||
 ≤200 DDD | 24 | 0.98 (0.65-1.48) | 0.97 (0.64-1.47) |
 201-796 DDD | 18 | 1.09 (0.68-1.74) | 1.19 (0.74-1.91) |
 >796 DDD | 23 | 1.31 (0.86-1.99) | 1.37 (0.90-2.09) |
Duration of warfarin use | |||
 ≤1 year | 20 | 0.91 (0.53-1.56) | 0.72 (0.42-1.24) |
 2-4 years | 22 | 0.96 (0.57-1.61) | 0.87 (0.52-1.47) |
 5 or more years | 23 | 1.33 (0.80-2.23) | 1.16 (0.69-1.94) |
Intensity of warfarin use | |||
 ≤114 DDD/year | 21 | 0.95 (0.56-1.62) | 0.79 (0.47-1.35) |
 115-200 DDD/year | 24 | 1.09 (0.65-1.81) | 0.94 (0.57-1.57) |
 >200 DDD/year | 20 | 1.10 (0.64-1.89) | 0.96 (0.56-1.65) |