From: VEGFR2 regulates endothelial differentiation of colon cancer cells
Viariant | Total | VEGFR2 expression | χ2 | P value | ||
---|---|---|---|---|---|---|
Negative (%) | Weak expression (%) | Strong expression (%) | ||||
Age | ||||||
  < 45 | 27 | 7(25.9) | 12(44.4) | 8 (29.6) | 1.651 | 0.438 |
  ≥ 45 | 176 | 28 (15.9) | 70(51.1) | 58 (33.0) | ||
Sex | ||||||
 Male | 91 | 12(13.2) | 46(50.5) | 33 (36.3) | 2.290 | 0.318 |
 Female | 112 | 23 (20.5) | 56(50.0) | 33(29.5) | ||
Tumor size | ||||||
  ≥ 5 cm | 67 | 15 (22.4) | 31(46.3) | 21(31.3) | 1.893 | 0.388 |
  < 5 cm | 136 | 20(14.7) | 71(52.2) | 45(33.1) | ||
Histological differentiation | ||||||
 Well differentiated | 14 | 4 (28.6) | 8(57.1) | 2 (14.3) | 32.110 | <0.001* |
 Moderately differentiated | 101 | 19(18.8) | 65(64.4) | 17(16.8) | ||
 Poorly differantiated | 88 | 12(13.6) | 29(33.0) | 47 (53.4) | ||
Clinical stage | ||||||
 TNMI | 7 | 1(14.3) | 4(57.1) | 2(28.6) | 7.518 | 0.276 |
 TNMII | 127 | 21(17.3) | 71(55.9) | 34(26.8) | ||
 TNMIII | 58 | 11(19.0) | 23(39.7) | 24(41.4) | ||
 TNMIV | 11 | 1 (9.1) | 4(36.4) | 6(54.5) | ||
Metastasis | ||||||
 Absent | 129 | 22(17.1) | 76(58.9) | 31 (24.0) | 13.129 | 0.001* |
 Present | 74 | 13(17.6) | 26(35.1) | 35 (47.3) |