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Table 1 Correlation between VEGFR2 and clinicopathologic characteristics of patients with colon cancer

From: VEGFR2 regulates endothelial differentiation of colon cancer cells

Viariant

Total

VEGFR2 expression

χ2

P value

Negative (%)

Weak expression (%)

Strong expression (%)

Age

  < 45

27

7(25.9)

12(44.4)

8 (29.6)

1.651

0.438

  ≥ 45

176

28 (15.9)

70(51.1)

58 (33.0)

Sex

 Male

91

12(13.2)

46(50.5)

33 (36.3)

2.290

0.318

 Female

112

23 (20.5)

56(50.0)

33(29.5)

Tumor size

  ≥ 5 cm

67

15 (22.4)

31(46.3)

21(31.3)

1.893

0.388

  < 5 cm

136

20(14.7)

71(52.2)

45(33.1)

Histological differentiation

 Well differentiated

14

4 (28.6)

8(57.1)

2 (14.3)

32.110

<0.001*

 Moderately differentiated

101

19(18.8)

65(64.4)

17(16.8)

 Poorly differantiated

88

12(13.6)

29(33.0)

47 (53.4)

Clinical stage

 TNMI

7

1(14.3)

4(57.1)

2(28.6)

7.518

0.276

 TNMII

127

21(17.3)

71(55.9)

34(26.8)

 TNMIII

58

11(19.0)

23(39.7)

24(41.4)

 TNMIV

11

1 (9.1)

4(36.4)

6(54.5)

Metastasis

 Absent

129

22(17.1)

76(58.9)

31 (24.0)

13.129

0.001*

 Present

74

13(17.6)

26(35.1)

35 (47.3)

  1. *Significantly different