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Table 1 The association of miRNA-148a, miRNA-625-3p and tumor budding with clinical and pathological characteristics

From: Down-regulation of miRNA-148a and miRNA-625-3p in colorectal cancer is associated with tumor budding

Characteristic

N

miRNA 148-a expression

miRNA 625-3p expression

Tumor budding

  

Low

High

p

Low

High

p

Yes

No

p

Total

54

27

27

 

27

27

 

21

33

 

Age

 < 65

28

17

12

0.172

15

13

0.586

14

15

0.128

 ≥ 65

26

10

15

12

14

7

18

Gender

 Female

26

13

13

1.000

13

13

1.000

12

14

0.291

 Male

28

14

14

14

14

9

19

Location

 C18–19

34

15

19

0.260

13

21

0.024

11

23

0.199

 C20

20

12

8

14

6

10

10

Side

 Right

12

6

6

1.000

5

7

0.513

7

5

0.117

 Left

42

21

21

22

20

14

28

T

 1–3

36

17

19

0.564

16

20

0.248

14

22

1.000

 4

18

10

8

11

7

7

11

N

 0–1

34

15

19

0.260

16

18

0.573

11

23

0.199

 2

20

12

8

11

9

10

10

Extrahepatic metastases

 Yes

33

15

19

0.260

15

18

0.402

14

19

0.402

 No

21

12

8

12

9

7

14

Number of metastatic sites

 1–2

39

20

19

0.762

22

17

0.129

15

24

0.917

 ≥ 3

15

7

8

5

10

6

9

Type of adenocarcinoma

 Adenocarcinoma

43

24

19

0.091

24

19

0.311

18

25

0.376

 Mucinous

11

3

8

4

7

3

8

Tumor budding

 Yes

21

14

7

0.051

14

7

0.051

-

-

-

 No

33

13

20

13

20

-

-

KRAS

 Mutated

37

18

19

0.770

17

20

0.379

15

22

0.713

 Wild type

17

9

8

10

7

6

11