Distinct preoperative clinical features predict four histopathological subtypes of high-grade serous carcinoma of the ovary, fallopian tube, and peritoneum

Table 1 Clinical features among the four pathological subtypes of HGSC

Pathological subtype		IR	PG	SP	MT
FIGO stage
Early (Stage I & II)		8	2	2	0
Advanced (Stage III & IV)		9	5	12	27
P value		0.0013*	0.6043	1.0000	0.0008*
Location of main tumor in MRI
Ovary or Fallopian tube		17	5	13	18
Peritoneum		0	2	1	9
P value		0.0269*	0.6043	0.4364	0.0202*
Morphology of main tumor in MRI
Solid		11	4	11	21
Cystic		6	3	3	6
P value		0.5299	0.3853	0.7402	0.5748
The amount of ascites in MRI
Small		14	5	5	7
Large		3	2	9	20
P value		0.0014*	0.2440	0.3750	0.0052*
Peritoneal lesion in MRI
Presence	Negative	9	4	3	1
Presence	Positive	8	3	11	26
P value		0.0080*	0.0700	0.7448	0.0004*
Pattern	Sporadic	6	0	4	2
Pattern	Diffuse	2	3	7	24
P value		0.0016*	0.5629	0.4304	0.0059*
Omental cake in CT
Negative		10	4	5	5
Positive		7	3	9	22
P value		0.0416*	0.4080	1.0000	0.0179*
radiographically enlarged lymph nodes in CT
Negative		9	7	5	21
Positive		8	0	9	6
P value		0.2554	0.0452*	0.0243*	0.0717
Distant metastasis in CT
Negative		17	7	11	17
Positive		0	0	3	10
P value		0.0146*	0.3287	1.0000	0.0053*

P value: Fisher’s exact test, comparing between each subtype and the other subtypes, * p < 0.05

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