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Table 2 Diagnostic summary of NSE for malignant pleural effusion

From: Is neuron-specific enolase useful for diagnosing malignant pleural effusions? evidence from a validation study and meta-analysis

 

MPE

SCLC-MPE

 

Serum NSE

Pleural NSE

Pleural/serum NSE ratio

Serum NSE

Pleural NSE

Pleural/serum NSE ratio

Cut-off

12.29 ng/ml

8.92 ng/ml

0.39

12.29 ng/ml

17.42 ng/ml

0.60

Sensitivity

66.91%

59.56%

79.41%

100%

100%

100%

Specificity

62.75%

83.33%

57.84%

62.75%

92.16%

69.60%

AUC

0.65

0.76

0.68

0.86

0.99

0.92

  1. AUC Area under the curve, MPE Malignant pleural effusion, NSE Neuron-specific enolase, SCLC Small cell lung cancer
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BMC Cancer

ISSN: 1471-2407

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