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Table 1 The demographics characteristics and biochemical results of patients

From: Is neuron-specific enolase useful for diagnosing malignant pleural effusions? evidence from a validation study and meta-analysis

  Benign pleural effusion Malignant pleural effusion p value
No. of Patient 102 136  
Sex(male/female) 68/34 74/62 0.056
Age (years) 56 ± 19 58 ± 13 0.167
Pleural NSE (ng/ml) 6.41 ± 6.95 18.53 ± 27.30 <0.001
Pleural NSE (ng/mg of pleural protein) 0.15 ± 0.16 0.51 ± 0.88 <0.001
Pleural protein(g/l) 42.02 ± 13.04 41.84 ± 10.62 0.906
Pleural glucose (mmol/l) 5.84 ± 1.71 5.48 ± 2.51 0.216
Pleural LDH (U/l) 256.57 ± 181.22 502.99 ± 414.15 <0.001
Pleural LDH (U/g of pleural protein) 5.79 ± 3.95 13.68 ± 14.96 <0.001
Serum NSE (ng/ml) 13.77 ± 13.33 19.51 ± 16.54 0.004
Serum NSE (ng/mg of pleural protein) 0.39 ± 0.63 0.54 ± 0.61 0.067
Pleural/serum NSE ratio 0.56 ± 0.55 1.08 ± 1.54 0.001
  1. LDH Lactic Dehydrogenase, NSE Neuron-specific enolase