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Table 1 Correlations between NAT10 expression in HCCs and the clinicopathologic factors

From: NAT10 is upregulated in hepatocellular carcinoma and enhances mutant p53 activity

 

NAT10 expression level (Score)

 

0

1

2

3

Total

p

Age (years)

<=60

9

6

15

59

89

0.598

>60

2

1

8

19

30

Tumor Size (cm)

<5

10

6

13

33

62

0.005

> = 5

1

1

10

45

57

Serum AFP (ng/ml)

<=20

4

5

10

27

46

0.266

>20

7

2

13

51

73

Tumor Number

=1

10

7

20

60

97

0.287

>1

1

0

3

18

22

Lymph node metastasis

No

11

7

21

75

114

0.579

Yes

0

0

2

3

5

Tumor encapsulation

No

8

2

13

35

58

0.195

Yes

3

5

10

43

61

Vascular invasion

No

11

7

18

52

88

0.033

Yes

0

0

5

26

31

Edmondson-Steiner grade

ES = 1 ~ 2

8

6

19

55

88

0.597

ES = 3 ~ 4

3

1

4

23

31

  1. NAT10 expression was determined in 119 HCCs samples by immunohistochemistry as described in the Methods. The correlations between the expression levels of NAT10 and clinico-pathological factors of HCCs were evaluated by the Mann-Whitney U test. We concluded that NAT10 expression was correlated with tumor size and vascular invasion (p < 0.05). However, NAT10 expression was not correlated with other factors such as age, α-fetoprotein (AFP) levels, capsular formation, tumor number, margin status, and Edmondson-Steiner grade