Fig. 2

Selected features of biomarker expression. a T2 tongue SCC (T). Expression of uPAR, TF and EGFR confined to the tumor compartment. b An example of strong TF expression on the neoplastic cells at the invasive front of a tongue SCC (T). c An example of a tongue SCC T) invading deeply into the underlying stroma. Black arrows indicate expression of CK and uPAR on small tumor cell groups and the white square shows the location of the enlarged region of interest depicted in panel (d)