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Table 2 Characterization of the anthropometric and biochemical variables evaluated according to the groups established by the duration of tamoxifen use (n = 84)

From: Temporal influence of endocrine therapy with tamoxifen and chemotherapy on nutritional risk and obesity in breast cancer patients

Variables

 

Mean ± SD

 

Total (n = 84)

Group 1 (n = 32)

Group 2 (n = 22)

Group 3 (n = 30)

p-value

Age (range: 33–73 years)

 

53.11 ± 8.73

51.37 ± 7.35

54.09 ± 9.18

54.23 ± 9.69

0.37

Anthropometric

 Current BMI (Kg/m2)

  Adults (n = 62)

 

26.79 ± 4.59

28.38 ± 4.12

26.76 ± 4.29

24.54 ± 4.73

0.018

  Elderly (n = 22)

 

28.16 ± 4.53

29.40 ± 7.87

27.30 ± 2.07

28.07 ± 3.86

0.760

  WC (cm)

 

90.63 ± 11.07

93.11 ± 10.07

91.67 ± 10.83

87.21 ± 11.73

0.096

  BFP (n = 74)

 

35.23 ± 7.55

35.55 ± 7.53

34.38 ± 7.45

35.54 ± 7.92

0.845

Biochemicals

Recommendation

     

 TG

<150 mg/dL

153.49 ± 85.21

156.43 ± 86.51

181.45 ± 102.83

130.03 ± 62.97

0.095

 HDL-C

>60 mg/dL

55.19 ± 17.92

53.34 ± 16.62

47.51 ± 19.751

62.78 ± 15.291

0.006

 LDL-C

<100 mg/dL

96.80 ± 28.24

94.79 ± 25.18

99.06 ± 37.88

97.30 ± 23.61

0.858

 Blood glucose

<100 mg/dL

82.17 ± 30.22

78.41 ± 35.90

86.00 ± 29.02

83.37 ± 24.47

0.644

 Hemoglobin

12.0 a 15.5 g/dL

12.88 ± 1.69

12.63 ± 2.54

13.00 ± 0.80

13.05 ± 0.83

0.582

 WBC

3.500 a 10.500 mil/mm

5916.55 ± 1737.62

5403.12 ± 1589.95

6232.27 ± 1508.85

6232.67 ± 1954.68

0.104

 Platelets

150 a 450 mil/mm

194,142.9 ± 65,099.0

185,062.50 ± 73,578.98

198,772.73 ± 68,529.40

200,433.33 ± 52.848.31

0.608

 CRP

<0.3 mg/dL

0.42 ± 0.64

0.49 ± 0.98

0.37 ± 0.31

0.37 ± 0.30

0.698

Food consumption

 Energy (kcal)

 

1591.63 ± 526.80

1742.62 ± 580.622

1393.56 ± 449.092

1575.83 ± 482.39

0.054

 Energy (kJ)

 

6659.38 ± 2204.13

7291,12 ± 2429,312

5830,66 ± 1878,992

6593,27 ± 2018,32

0.054

 Carbohydrate (g)

 

201.94 ± 71.98

212.01 ± 67.38

182.85 ± 63.47

205.19 ± 81.60

0.331

 Protein (g)

 

65.09 ± 25.02

72.14 ± 28.63

56.66 ± 21.86

63.76 ± 21.42

0.076

 Lipids (g)

 

58.37 ± 22.69

66.74 ± 25.933

48.61 ± 18.143

56.61 ± 19.06

0.012

  1. BMI body mass index, WC waist circumference, TG triglycerides, HDL-C high density lipoprotein, LDL-C low density lipoprotein, WBC white blood cell count, CRP C Reactive Protein, SD standard deviation, Group 1 women using tamoxifen for the first 3 years, Group 2 women using tamoxifen between 3 and 4 years, Group 3 women using TMX for more than 4 years. The cutoff points of the biochemicals parameters were evaluated according to recommendations [37,38,39]; p < 0.05 was considered significant, calculated by ANOVA
  2. 1 p = 0.006; 2 p = 0.049; 3 p = 0.010
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