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Table 1 Baseline characteristics according to the new score, which uses the neutrophil-to-lymphocyte ratios in serum and malignant pleural effusion (smNLR score) in lung cancer patients

From: Prognostic impact of a new score using neutrophil-to-lymphocyte ratios in the serum and malignant pleural effusion in lung cancer patients

Variable Total smNLR score P value
n = 158 0 (n = 84) 1 (n = 58) 2 (n = 16)
Age, years      0.246
  < 65
  ≥ 65
60 (38.0)
98 (62.0)
37 (44.0)
47 (56.0)
18 (31.0)
40 (69.0)
5 (31.3)
11 (68.7)
 
Sex      0.167
 Male
 Female
81 (51.3)
77 (48.7)
40 (47.6)
44 (52.4)
35 (60.3)
23 (39.7)
6 (37.5)
10 (62.5)
 
Smoking habit      0.391
 Current + Former
 Never
85 (53.8)
73 (46.2)
43 (51.2)
41 (48.8)
35 (60.3)
23 (39.7)
7 (43.8)
9 (56.2)
 
ECOG PS      0.001
 0–1
 2–4
94 (59.5)
64 (40.5)
61 (72.6)
23 (27.4)
28 (48.3)
30 (51.7)
5 (31.3)
11 (68.7)
 
Histology      0.023
 ADC
 SQC
 Others
 SCC
135 (85.4)
9 (5.7)
5 (3.2)
9 (5.7)
77 (91.6)
4 (4.8)
0 (0.0)
3 (3.6)
48 (82.8))
2 (3.4)
4 (6.9)
4 (6.9)
10 (62.5)
3 (18.8)
1 (6.2)
2 (12.5)
 
M Stage      0.002
 M1a
 M1b
76 (48.1)
82 (51.9)
51 (60.7)
33 (39.3)
21 (36.2)
37 (63.8)
4 (25.0)
12 (75.0)
 
Treatment      0.056
 Supportive
 Active
74 (46.8)
84 (53.2)
32 (38.1)
52 (61.9)
32 (55.2)
26 (44.8)
10 (62.5)
6 (37.5)
 
Hemoglobin, g/dLa      0.170
  < 12
  ≥ 12
59 (37.3)
99 (62.7)
27 (32.1)
57 (67.9)
23 (39.7)
35 (60.3)
9 (56.2)
7 (43.8)
 
Albumin, g/dLa      <0.001
  < 3.1
  ≥ 3.1
30 (19.0)
128 (81.0)
7 (8.3)
77 (91.7)
15 (25.9)
43 (74.1)
8 (50.0)
8 (50.0)
 
LDH, IU/La      0.261
  ≤ 211
  > 211
76 (48.1)
82 (51.9)
45 (53.6)
39 (46.4)
23 (39.7)
35 (60.3)
8 (50.0)
8 (50.0)
 
Calcium, mg/dLa      0.140
  ≤ 10.8
  > 10.8
156 (98.7)
2 (1.3)
83 (98.8)
1 (1.2)
58 (100)
0 (0.0)
15 (93.7)
1 (6.3)
 
sNLR      <0.001
  < 3.85
  ≥ 3.85
87 (55.1)
71 (44.9)
84 (100)
0 (0.0)
3 (5.2)
55 (94.8)
0 (0.0)
16 (100)
 
mNLR      <0.001
  < 1.36
  ≥ 1.36
139 (88.0)
19 (12.0)
84 (100)
0 (0.0)
55 (94.8)
3 (5.2)
0 (0.0)
16 (100)
 
  1. Data in parentheses are percentages
  2. Abbreviations: ECOG PS Eastern Cooperative Oncology Group performance status, ADC adenocarcinoma, SQC squamous cell carcinoma, SCC small cell carcinoma, LDH lactate dehydrogenase, sNLR neutrophil-to-lymphocyte ratio of serum, mNLR neutrophil-to-lymphocyte ratio of malignant pleural effusion
  3. aDichotomized by cutoff of normal value