Skip to main content

Advertisement

Table 4 Effect modification of association between active smoking and breast cancer in 21,831 women in the Danish Nurse Cohort by menopausal status, obesity, alcohol consumption and hormone therapy use

From: Active smoking and risk of breast cancer in a Danish nurse cohort study

    Never Former Current Ever
N No. of cases HR (95% CI) HR (95% CI) HR (95% CI) HR (95% CI)
Menopausal status
 Premenopausal 9455 466 1.00 1.03 (0.82–1.29) 1.30 (1.04–1.61) 1.16 (0.95–1.40)
 Postmenopausal 12,376 696 1.00 1.12 (1.92–1.37) 1.27 (1.05–1.52) 1.20 (1.02–1.42)
p-value      0.77 0.80
BMI
 Not obese (< 30 kg/m2) 20,578 1086 1.00 1.07 (0.92–1.25) 1.25 (1.08–1.45) 1.11 (1.03–1.33)
 Obese (≥ 30 kg/m2) 1253 76 1.00 1.23 (0.72–2.09) 1.47 (0.81–2.66) 1.32 (0.82–2.12)
p-value      0.84 0.63
Alcohol Consumption
 None 3320 183 1.00 1.11 (0.77–1.61) 1.17 (0.83–1.66) 1.14 (0.85–1.54)
 Moderate (1–14 drinks/week) 13,533 670 1.00 1.13 (0.94–1.37) 1.26 (1.05–1.52) 1.19 (1.02–1.40)
 Heavy (>14 drinks/week) 4978 309 1.00 0.96 (0.70–1.31) 1.34 (1.01–1.77) 1.17 (0.90–1.52)
p-value      0.66 0.99
Hormone therapy use
 Never 15,880 755 1.00 1.05 (0.88–1.26) 1.21 (1.02–1.44) 1.13 (0.97–1.32)
 Ever 5951 407 1.00 1.15 (0.88–1.49) 1.36 (1.06–1.73) 1 26 (1.01–1.58)
p-value      0.63 0 33