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Table 4 The univariate and multivariate analyses of the prognostic factors for survival

From: Prognostic significance of the total number of harvested lymph nodes for lymph node-negative gastric cancer patients

  Univariate HR (95% CI) P-value Multivariate HR (95% CI) P-value
Sex   0.138   
 Male 1    
 Female 1.462 (0.883, 2.421)    
BMI   0.437   
 <19 1    
 ~ < 25 0.901 (0.383, 2.116)    
 ~ < 30 0.671 (0.258, 1.745)    
 ≥30 0.891 (0.128, 1985)    
Differentiation   0.284   
 Well 1    
 Moderate 2.063 (0.495, 8.587)    
 Poor 2.669 (0.637, 11.188)    
LVI   0.659   
 No 1    
 Yes 1.336 (0.681, 2.622)    
Postoperative hospital stay 1.004 (0.996, 1.013) 0.335   
Reoperation   0.247   
 No 1    
 Yes 1.959 (0.614, 6.246)    
Tumour size   0.013   0.643
 ≤5 cm 1   1  
 >5 cm 2.088 (1.151, 3.789)   1.174 (0.596, 2.314)  
Gastrectomy   <0.001   0.707
 Distal 1   1  
 Proximal 2.565 (1.392, 4.728)   1.267 (0.649, 2.473)  
 Total 2.746 (1.555, 4.848)   1.267 (0.665, 2.413)  
 Blood loss volume 1.001 (1.001, 1.002) 0.001 1.001 (0.999, 1.002) 0.296
Complication   0.013   0.332
 No 1   1  
 Yes 2.122 (1.157, 3.890)   1.387 (0.716, 2.686)  
Age   0.009   0.031
 ≤60 1   1  
 >60 1.918 (1.169, 3.148)   1.830 (1.058, 3.165)  
NACT   0.002   0.093
 No 1   1  
 Yes 2.133 (1.310, 3.473)   1.600 (0.924, 2.771)  
T stagea   <0.001   <0.001
 T1 1   1  
 T2 4.126 (1.486, 11.461)   3.930 (1.378, 11.209)  
 T3 6.065 (2.463, 16.435)   5.089 (2.456, 15.364)  
 T4 8.092 (3.211, 20.391)   7.946 (3.065, 20.691)  
Operation duration 1.006 (1.003, 1.008) <0.001 1.007 (1.004, 1.010) <0.001
Total number of HLNs   0.047   0.002
N < 22 1   1  
N ≥ 22 0.618 (0.383, 0.999)   0.437 (0.262, 0.730)  
  1. HLNs harvested lymph nodes, HR hazard ratio, CI confidence interval, BMI body mass index, LVI lymphovascular invasion, NACT neoadjuvant chemotherapy
  2. a7th AJCC TNM staging system for gastric cancer