| |
1st Line
|
Maintenance
| | | | |
|---|
| |
Mean
|
95% CI
|
Mean
|
95% CI
|
Diff.
|
95% CI
|
F-value
|
p-value
|
|---|
|
Dyspnoea
|
23.0
|
19.9-26.0
|
21.2
|
0.0-45.4
|
1.73
|
−22.6-26.1
|
0.230
|
0.632
|
|
Coughing
|
31.1
|
27.8-34.4
|
26.7
|
21.4-32.0
|
4.4
|
−1.8-10.6
|
1.943
|
0.165
|
|
Haemoptysis
|
2.8
|
1.1-4.5
|
<0.1
|
0.0-10.5
|
2.8
|
−7.8-13.4
|
0.273
|
0.603
|
|
Sore mouth
|
8.0
|
5.5-10.4
|
7.0
|
2.9-11.1
|
1.0
|
−3.7-5.8
|
0.183
|
0.670
|
|
Dysphagia
|
9.1
|
6.8-11.4
|
6.1
|
1.7-10.6
|
3.0
|
−2.0-8.0
|
1.408
|
0.237
|
|
Peripheral neuropathy
|
14.9
|
11.8-18.0
|
18.8
|
13.7-23.9
|
−3.9
|
−9.9-2.0
|
1.711
|
0.192
|
|
Alopecia
|
10.2
|
7.3-13.0
|
21.7
|
16.6-26.8
|
−11.5
|
−17.4- -5.7
|
15.116
|
<0.001
|
|
Pain in chest
|
13.2
|
10.8-15.7
|
8.0
|
4.3-11.7
|
5.3
|
0.8-9.7
|
5.437
|
0.022
|
|
Pain in arm or shoulder
|
18.1
|
14.8-21.3
|
19.6
|
14.6-24.7
|
−1.6
|
−7.6-4.4
|
0.266
|
0.607
|
|
Pain in other parts
|
24.9
|
21.0-28.9
|
25.2
|
18.3-32.0
|
−0.2
|
−8.1-7.6
|
0.004
|
0.951
|
|
Taste Alterationsa
|
19.7
|
16.1-23.2
|
31.4
|
24.3-38.4
|
−11.7
|
−19.6- -3.7
|
8.442
|
0.004
|
|
Skin Toxicitya
|
18.1
|
15.0-21.3
|
16.9
|
12.0-21.8
|
1.2
|
−4.6-7.0
|
0.179
|
0.673
|
-
95% CI 95% confidence interval; Bold type indicates p <.05
-
aitems from the EORTC item bank
