| |
1st Line
|
Maintenance
| | | | |
|---|
| |
Mean
|
95% CI
|
Mean
|
95% CI
|
Diff.
|
95% CI
|
F-value
|
p-value
|
|---|
|
Physical Functioning
|
73.5
|
70.7-76.3
|
73.8
|
69.1-78.6
|
−0.3
|
−5.8-5.2
|
0.014
|
0.906
|
|
Role Functioning
|
62.4
|
58.5-66.2
|
59.1
|
53.0-65.1
|
3.3
|
−3.9-10.4
|
0.817
|
0.367
|
|
Social Functioning
|
66.2
|
62.8-69.7
|
70.5
|
64.9-76.0
|
−4.2
|
−10.7-2.3
|
1.630
|
0.203
|
|
Emotional Functioning
|
65.0
|
62.1-67.9
|
68.9
|
64.0-73.7
|
−3.9
|
−9.5-1.8
|
1.826
|
0.178
|
|
Cognitive Functioning
|
80.0
|
77.4-82.6
|
82.8
|
78.5-87.1
|
−2.8
|
−7.8-2.2
|
1.194
|
0.276
|
|
Global Quality of Life
|
58.2
|
55.7-60.8
|
57.3
|
53.1-61.4
|
1.0
|
−3.9-5.8
|
0.156
|
0.693
|
|
Fatigue
|
45.8
|
42.4-49.2
|
41.2
|
35.7-46.8
|
4.6
|
−1.9-11.1
|
1.949
|
0.164
|
|
Nausea/Vomiting
|
13.5
|
11.0-16.0
|
8.2
|
5.3-11.1
|
5.3
|
1.5-9.1
|
7.663
|
0.006
|
|
Pain
|
27.0
|
23.6-30.3
|
24.4
|
18.8-30.0
|
2.6
|
−3.9-9.1
|
0.612
|
0.435
|
|
Dyspnea
|
29.6
|
25.8-33.3
|
35.9
|
29.9-42.0
|
−6.4
|
−13.4-0.7
|
3.202
|
0.076
|
|
Sleep Disturbances
|
39.1
|
35.1-43.2
|
21.4
|
15.7-27.1
|
17.8
|
10.8-24.7
|
25.480
|
<0.001
|
|
Appetite Loss
|
26.1
|
22.2-29.9
|
18.6
|
12.5-24.7
|
7.5
|
0.2-14.7
|
4.172
|
0.043
|
|
Constipation
|
17.3
|
13.9-20.6
|
10.5
|
6.2-14.9
|
6.7
|
1.2-12.2
|
5.862
|
0.017
|
|
Diarrhea
|
7.8
|
5.4-10.3
|
6.1
|
2.5-9.7
|
1.7
|
−2.6-6.1
|
0.627
|
0.430
|
|
Financial Impact
|
19.6
|
16.3-23.0
|
23.6
|
17.9-29.3
|
−4.0
|
−10.6-2.6
|
1.426
|
0.234
|
|
QLQ-C30 Summary Score
|
71.8
|
69.7-73.9
|
75.7
|
72.4-79.0
|
−3.9
|
−7.9-0.0
|
3.948
|
0.048
|
-
95% CI 95% confidence interval; Bold type indicates p <.05
