Table 3 Univariate and multivariate analysis of factors associated with survival in HCC patients (n = 174)
OS | ||||||
|---|---|---|---|---|---|---|
Univariate analysis | Multivariate analysis | |||||
HR | 95% CI | P | HR | 95% CI | P | |
Gender (Female vs. Male) | 0.755 | 0.415–1.374 | 0.354 | |||
Age, years (≤ 50 vs. > 50) | 1.382 | 0.878–2.177 | 0.159 | |||
HBsAg (Negative vs. Positive) | 2.922 | 1.067–8.003 | 0.028* | 2.729 | 0.994–7.491 | 0.051 |
Child-Pugh classification (A vs. B) | 1.669 | 0.609–4.577 | 0.320 | |||
Serum AFP, ng/ml (≤ 20 vs. > 20) | 1.133 | 0.689–1.863 | 0.62 | |||
Tumor Number (Single vs. Multiple) | 1.638 | 0.953–2.814 | 0.07 | |||
Tumor size, cm (≤ 5 vs. > 5) | 2.429 | 1.455–4.056 | < 0.001* | 1.888 | 1.121–3.179 | 0.017* |
Tumor capsule (No/ incomplete vs. Yes) | 0.662 | 0.421–1.042 | 0.072 | |||
Vascular invasion (N0 vs. Yes) | 2.126 | 0.976–4.634 | 0.051 | |||
Liver cirrhosis (Absent vs. Present) | 1.097 | 0.592–2.035 | 0.767 | |||
Differentiation grade (I / II vs. III/IV) | 1.348 | 0.856–2.125 | 0.194 | |||
TNM stage (I vs. II/III) | 1.968 | 1.222–3.171 | 0.004* | 1.558 | 0.961–2.528 | 0.072 |
KOR (Positive vs. Negative) | 0.499 | 0.387–0.642 | < 0.001* | 0.526 | 0.408–0.679 | < 0.001* |