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Table 1 Correlation of KOR mRNA expression with clinicopathological features in HCC (n = 64)

From: Down-regulation of the tumour suppressor κ-opioid receptor predicts poor prognosis in hepatocellular carcinoma patients

Variables

Cases

KOR mRNA

T < N (n = 51)

T ≥ N (n = 13)

P

Gender

 Female

8

5

3

0.196

 Male

56

46

10

Age, years

 ≤ 50

28

22

6

0.845

 > 50

36

29

7

HBsAg

 Negative

8

6

2

0.725

 Positive

56

45

11

Child-Pugh classificationa

 A

61

49

12

0.566

 B

3

2

1

Serum AFP, ng/ml

 ≤ 20

30

21

9

0.070

 > 20

34

30

4

Tumor Number

 Single

48

37

11

0.370

 Multiple

16

14

2

Tumor size, cm

 ≤ 5

35

24

11

0.015*

 > 5

29

27

2

Tumor capsule

 No/incomplete

31

23

8

0.290

 Yes

33

28

5

Vascular invasion

 No

58

46

12

0.816

 Yes

6

5

1

Liver cirrhosis

 Absent

11

7

4

0.146

 Present

53

44

9

Differentiation grade

 I / II

34

23

11

0.011*

 III/IV

30

28

2

TNM stage

 I

36

25

11

0.021*

 II/III

28

26

2

  1. The data are reported as number. P-values were obtained from the chi-square test. aNo patient with Child-Pugh class C was found. *Statistical significance was set to P < 0.05
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BMC Cancer

ISSN: 1471-2407

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