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Table 2 Analysis of risk factors for any positive ALNs

From: Development of nomograms to predict axillary lymph node status in breast cancer patients

 

Univariate analysis

Multivariate analysis

 

N0

N1–3

P b

OR(95%)

P

 

n

%a

n

%a

Age Group

 Age < =50Yrs

15,652

67.38

7579

32.62

<0.001

1

 

 50-60Yrs

18,757

72.23

7210

27.77

0.91(0.87–0.95)

<0.001

  > 60Yrs

39,253

77.85

11,167

22.15

0.70(0.67–0.73)

<0.001

Location Of Lesions

 UIQ

15,519

82.15

3372

17.85

<0.001

1

 

 UOQ

38,406

71.96

14,966

28.04

1.84(1.75–1.93)

<0.001

 LOQ

8149

71.33

3276

28.67

1.91(1.79–2.03)

<0.001

 LIQ

7089

78.02

1997

21.98

1.46(1.36–1.56)

<0.001

 Central

4499

65.74

2345

34.26

2.19(2.03–2.35)

<0.001

T-Stage

 T1

57,744

83.23

11,631

16.77

<0.001

1

 

 T2

15,160

54.78

12,515

45.22

3.05(2.95–3.16)

<0.001

 T3

758

29.52

1810

70.48

7.85(7.12–8.65)

<0.001

Histology

 IDC

55,824

73.48

20,150

26.52

<0.001

1

 

 ILC

6174

71.94

2408

28.06

1.08(1.02–1.15)

0.009

 IDC & ILC

3437

68.67

1568

31.33

1.19(1.11–1.28)

<0.001

 IDC & Others

2688

80.02

671

19.98

0.74(0.67–0.82)

<0.001

 IMC

1731

93.62

118

6.38

0.24(0.19–0.29)

<0.001

 Others

3808

78.53

1041

21.47

0.79(0.73–0.86)

<0.001

Grade

 I

21,746

84.74

3917

15.26

<0.001

1

 

 II

32,129

73.17

11,779

26.83

1.29(1.23–1.35)

<0.001

 III

19,337

65.73

10,083

34.27

1.31(1.24–1.38)

<0.001

 Others/NA

450

71.77

177

28.23

1.27(1.04–1.56)

0.022

Estrogen Receptor

 Negative

11,326

71.93

4420

28.07

<0.001

1

 

 Positive

62,336

74.32

21,536

25.68

1.20(1.12–1.28)

<0.001

Progesterone Receptor

 Negative

18,233

72.70

6847

27.30

<0.001

1

 

 Positive

55,429

74.36

19,109

25.64

1.16(1.10–1.23)

<0.001

Her2

 Negative

65,656

74.89

22,014

25.11

<0.001

1

 

 Positive

8006

67.01

3942

32.99

1.11(1.05–1.16)

<0.001

Lymphovascular Invasion

 Not Present

66,799

82.82

13,858

17.18

<0.001

1

 

 Present

6863

36.20

12,098

63.80

6.36(6.12–6.60)

<0.001

  1. ALN axillary lymph node, Yrs years old, HER2 human epidermal growth factor receptor 2, LIQ lower-inner quadrant, LOQ lower-outer quadrant, UIQ Upper-inner quadrant, UOQ Upper-outer quadrant, N/A not available, IDC infiltrating ductal carcinoma, ILC infiltrating lobular carcinoma, IMC invasive mucinous carcinoma, NS non-significant
  2. aRow percentage was shown
  3. bChi-square test was used for univariate analysis
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