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Table 2 Median 3-year overall survival (OS)/disease free survival (DFS) and median OS/DFS in months in previously diagnosed AEL patients depending on subtypes and cytogenetic risk group (MRC and IPSS criteria)

From: An analysis of 97 previously diagnosed de novo adult acute erythroid leukemia patients following the 2016 revision to World Health Organization classification

Parameter

Median

3-year OS

Median OS (Months)

P

Median

3-year DFS

Median DFS (Months)

P

Subtype

 MDS

56%

44.6

0.563

75.1%

n.r.

0.538

 AML

64.4%

n.r.

60.7%

n.r.

Cytogenetics

 Intermediate MRC category

62.2%

n.r

<0.0001

71.5%

n.r

0.008

 Unfavorable MRC category

12%

5.03

25%

5.3

 Good IPSS category

56.9%

n.r

0.045

69.3%

n.r

0.099

 Intermediate IPSS category

75%

n.r

85.7%

n.r

 Adverse IPSS category

13.3%

11.8

25%

5.33

  1. Abbreviation: IPSS International Prognostic Scoring System, MRC Medical Research Council