Characteristics | Renal cell carcinoma N = 7 (28.0%) | Other tumor types N = 18 (72.0%) | Patients N = 25 | |||
---|---|---|---|---|---|---|
Median Age, years (min-max) | 53.10 (43.80–71.20) | 62.55 (41.00–78.60) | 61.90 (41.00–78.60) | |||
Male | 5 | (71.4) | 9 | (50.0) | 14 | (56.0) |
History of hypertension | 3 | (42.9) | 6 | (33.3) | 9 | (36.0) |
Nephrectomy | 6 | (85.7) | 1 | (5.0) | 7 | (87.5) |
Localization | ||||||
Cervix cancer | 0 | - | 2 | (11.1) | 2 | (8.1) |
Colorectal cancer | 0 | - | 1 | (5.6) | 1 | (5.6) |
Melanoma | 0 | - | 4 | (22.2) | 4 | (16.0) |
Pancreatic cancer | 0 | - | 2 | (11.1) | 2 | (8.1) |
Breast cancer | 0 | - | 1 | (5.6) | 1 | (5.6) |
Adrenocortical carcinoma | 0 | - | 1 | (5.6) | 1 | (5.6) |
Seminoma | 0 | - | 1 | (5.6) | 1 | (5.6) |
Lung cancer | 0 | - | 1 | (5.6) | 1 | (5.6) |
Other (head and neck, thyroid, bladder, mesothelioma) | 0 | - | 5 | (27.8) | 5 | (25.0) |
M0 at diagnosis | 5 | (71.4) | 13 | (72.2) | 18 | (72.0) |
Time between diagnosis and first metastases | ||||||
Mean (std) | 11.86 (15–27) | 21.73 (23–56) | 18.85 (21–64) | |||
Median (min-max) | 12.88 (−1.28–43.20) | 16.29 (−0.39–80.06) | 13.14 (−1.28–80.06) | |||
Missing | 0 | 1 | 1 | |||
Time between diagnosis and first metastases | ||||||
≤ 12 months | 3 | (42.9) | 7 | (41.2) | 10 | (41.7) |
> 12 months | 4 | (57.1) | 10 | (58.8) | 14 | (58.3) |
Missing | 0 | 1 | 1 | |||
Number of metastatic sites | ||||||
1 | 5 | (71.4) | 12 | (70.6) | 17 | (70.8) |
> 1 | 2 | (28.6) | 5 | (29.4) | 7 | (29.2) |
Missing | 0 | 1 | 1 | |||
Median (min-max) | 1 (1–1) | 3 (1–6) | 3 (1–6) | |||
Number of prior therapy | ||||||
Chemotherapy | 1 | (14.3) | 18 | (100.0) | 19 | (76.0) |
Median number of previous chemotherapy (min-max) | 1 (1–1) | 3 (1–6) | 3 (1–6) | |||
Bevacizumab | 0 | (0.0) | 1 | (5.6) | 1 | (5.3) |
Radiotherapy | 3 | (42.9) | 13 | (72.2) | 16 | (64.0) |
Hemoglobin | ||||||
< 115 g/L (F), <130 g/L (M) | 1 | (14.3) | 7 | (38.9) | 8 | (32.0) |
≥ 115 g/L (F), ≥130 g/L (M) | 6 | (85.7) | 11 | (61.1) | 17 | (68.0) |
Serum creatinine (μmol/L) | ||||||
Median (min-max) | 97.5 (84.0–127.0) | 79.5 (49.0–127.0) | 84.0 (49.0–127.0) | |||
Missing | 1 | 0 | 1 | |||
AST (UI/L) | ||||||
Median (min-max) | 17.0 (16.0–21.0) | 33.0 (13.0–84.0) | 24.0 (13.0–84.0) | |||
Missing | 1 | 0 | 1 | |||
ALT (UI/L) | ||||||
Median (min-max) | 21.0 (10.0–34.0) | 28.0 (8.0–52.0) | 26.0 (8.0–52.0) | |||
Missing | 1 | 0 | 1 | |||
LDH > normal | 2 | (28.6) | 10 | (55.6) | 12 | (48.0) |