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Table 1 Number of GOT1-bearing mice used in each analysis after treatment with sonidegib, 177Lu-octreotate, or a combination of both pharmaceuticals, and in control animals

From: Hedgehog inhibitor sonidegib potentiates 177Lu-octreotate therapy of GOT1 human small intestine neuroendocrine tumors in nude mice

 

Sonidegib

177Lu-octreotate

Sonidegib +177Lu-octreotate

Control

Tumor volume measurements

5

5a

5

6a

Dosimetric calculations

-

5

5

-

Gene expression analysis

3

3

3

3a

Protein expression analysis

3

3

3

3

  1. aData has been characterized in a previous publication [29]