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Table 4 Relationship between the GGT concentration and clinical characteristics of patients with ESCC

From: Prognostic value of pretreatment serum alanine aminotransferase/aspartate aminotransferase (ALT/AST) ratio and gamma glutamyltransferase (GGT) in patients with esophageal squamous cell carcinoma

Variables GGT
  Cases (n) ≥23.1 <23.1 p value* Mean ± SD p value**
Gender
 Male 343 184 158 0.004 37.96 ± 4.72 0.001
 Female 101 38 63   26.20 ± 1.84  
Age
  < 59 years 232 124 108 0.128 39.85 ± 5.20 0.056
  ≥ 59 years 212 98 114   30.29 ± 2.85  
Alcohol
 No 260 97 163 0.000 27.57 ± 3.06 0.000
 Yes 184 125 59   46.18 ± 5.37  
Tumor location
 Upper 40 21 19 0.009 40.24 ± 5.29 0.002
 Middle 276 123 153   30.05 ± 2.60  
 Lower 128 78 50   45.02 ± 6.22  
Stage
 I and II 234 106 128 0.037 29.81 ± 3.43 0.007
 III and IV 210 116 94   41.39 ± 4.98  
Treatment (n)
 Surgery only 236 102 134 0.013 31.64 ± 3.84 0.033
 Surgery and chemotherapy 178 106 72   39.09 ± 4.72  
 Surgery and radiotherapy 6 3 3   33.73 ± 3.20  
 Surgery and chemotherapy and radiotherapy 24 12 12   43.35 ± 4.81  
Deaths
 No 198 86 112 0.013 31.82 ± 3.83 0.034
 Yes 246 136 110   38.07 ± 4.58  
  1. Mean ± SD, Mean ± standard deviation
  2. *P values were calculated using the chi-squared test (χ2 test), p < 0.05 indicated significant differences
  3. **P values were calculated using unpaired Student’s t-tests or Mann–Whitney U test, p < 0.05 indicated significant differences