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Table 4 Relationship between the GGT concentration and clinical characteristics of patients with ESCC

From: Prognostic value of pretreatment serum alanine aminotransferase/aspartate aminotransferase (ALT/AST) ratio and gamma glutamyltransferase (GGT) in patients with esophageal squamous cell carcinoma

Variables

GGT

 

Cases (n)

≥23.1

<23.1

p value*

Mean ± SD

p value**

Gender

 Male

343

184

158

0.004

37.96 ± 4.72

0.001

 Female

101

38

63

 

26.20 ± 1.84

 

Age

  < 59 years

232

124

108

0.128

39.85 ± 5.20

0.056

  ≥ 59 years

212

98

114

 

30.29 ± 2.85

 

Alcohol

 No

260

97

163

0.000

27.57 ± 3.06

0.000

 Yes

184

125

59

 

46.18 ± 5.37

 

Tumor location

 Upper

40

21

19

0.009

40.24 ± 5.29

0.002

 Middle

276

123

153

 

30.05 ± 2.60

 

 Lower

128

78

50

 

45.02 ± 6.22

 

Stage

 I and II

234

106

128

0.037

29.81 ± 3.43

0.007

 III and IV

210

116

94

 

41.39 ± 4.98

 

Treatment (n)

 Surgery only

236

102

134

0.013

31.64 ± 3.84

0.033

 Surgery and chemotherapy

178

106

72

 

39.09 ± 4.72

 

 Surgery and radiotherapy

6

3

3

 

33.73 ± 3.20

 

 Surgery and chemotherapy and radiotherapy

24

12

12

 

43.35 ± 4.81

 

Deaths

 No

198

86

112

0.013

31.82 ± 3.83

0.034

 Yes

246

136

110

 

38.07 ± 4.58

 
  1. Mean ± SD, Mean ± standard deviation
  2. *P values were calculated using the chi-squared test (χ2 test), p < 0.05 indicated significant differences
  3. **P values were calculated using unpaired Student’s t-tests or Mann–Whitney U test, p < 0.05 indicated significant differences