Prognostic value of pretreatment serum alanine aminotransferase/aspartate aminotransferase (ALT/AST) ratio and gamma glutamyltransferase (GGT) in patients with esophageal squamous cell carcinoma

Table 3 Relationship between the LSR levels and clinical characteristics of patients with ESCC

Variables	LSR
	Cases (n)	≥0.82	<0.82	p value*	Mean ± SD	p value**
Gender (n)
Male	342	179	163	0.305	0.89 ± 0.34	0.165
Female	101	47	54		0.84 ± 0.27
Age
< 59 years	232	122	110	0.448	0.91 ± 0.35	0.092
≥ 59 years	211	104	107		0.85 ± 0.27
Alcohol
No	259	122	137	0.051	0.85 ± 0.31	0.024
Yes	184	104	80		0.92 ± 0.34
Tumor location
Upper	40	25	15	0.011	0.99 ± 0.39	0.038
Middle	275	131	175		0.86 ± 0.33
Lower	128	70	58		0.88 ± 0.28
Stage
I and II	234	125	109	0.284	0.89 ± 0.32	0.282
III and IV	209	101	108		0.87 ± 0.33
Treatment
Surgery only	236	117	119	0.397	0.85 ± 0.31	0.109
Surgery and chemotherapy	177	97	80		0.92 ± 0.34
Surgery and radiotherapy	6	3	3		0.89 ± 0.25
Surgery and chemotherapy and radiotherapy	24	9	15		0.81 ± 0.34
Deaths
No	198	120	78	0.000	0.96 ± 0.35	0.000
Yes	245	106	139		0.82 ± 0.29

Mean ± SD, Mean ± standard deviation
*P values were calculated using the chi-squared test (χ² test), p < 0.05 indicated significant differences
**P values were calculated using unpaired Student’s t-tests or Mann–Whitney U test, p < 0.05 indicated significant differences

ISSN: 1471-2407