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Table 6 Scenario analysis for men with low risk localised prostate cancer

From: The cost-effectiveness of active surveillance compared to watchful waiting and radical prostatectomy for low risk localised prostate cancer

Age at diagnosis (Years)

ICER (Cost per QALY gained)

Dominance

AS vs WW

RP vs WW

AS vs RP

RP vs AS

Scenario one: using the 5% conversion rate

 45

-

$6,441

-

-

AS was dominated by RP

 50

-

$7,908

-

-

AS was dominated by RP

 55

-

$10,361

-

-

AS was dominated by RP

 60

-

$14,021

-

-

AS was dominated by RP

 65

-

$21,226

-

-

AS was extended dominated by WW and RP

 70

$31,135

-

-

$33,140

-

Scenario two: using new quality of life inputs

 45

$11,060

-

-

-

RP was extended dominated by WW and AS

 50

$12,602

-

-

-

RP was extended dominated by WW and AS

 55

$14,814

-

-

-

RP was dominated by AS

 60

$17,807

-

-

-

RP was dominated by AS and by WW

 65

$21,916

-

-

-

RP was dominated by AS and by WW

 70

$26,833

-

-

-

RP was dominated by AS and by WW

Scenario three: using new costing inputs

 45

-

$5,324

-

-

AS was dominated by RP

 50

-

$6,613

-

-

AS was dominated by RP

 55

-

$8,793

-

-

AS was dominated by RP

 60

-

$12,332

-

-

AS was extended dominated by WW and RP

 65

$15,732

-

-

$24,000

-

 70

$19,364

-

-

$35,761

-

Scenario four: using new quality of life inputs and costing inputs

 45

$11,254

-

-

-

RP was extended dominated by WW and AS

 50

$12,882

-

-

-

RP was extended dominated by WW and AS

 55

$15,248

-

-

-

RP was extended dominated by WW and AS

 60

$18,520

-

-

-

RP was dominated by AS and by WW

 65

$23,184

-

-

-

RP was dominated by AS and by WW

 70

$30,122

-

-

-

RP was dominated by AS and by WW

Scenario five: using new quality of life values, costing values and the 5% conversion rate

 45

$22,904

-

-

-

RP was extended dominated by WW and AS

 50

$27,385

-

-

-

RP was extended dominated by WW and AS

 55

$33,790

-

-

-

RP was extended dominated by WW and AS

 60

$44,090

-

-

-

RP was dominated by WW

 65

$59,769

-

-

-

RP was dominated by WW and by AS

 70

$101,360

-

-

-

RP was dominated by WW and by AS

  1. RP radical prostatectomy, AS active surveillance, WW watchful waiting