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Fig. 4 | BMC Cancer

Fig. 4

From: Live-cell calcium imaging of adherent and non-adherent GL261 cells reveals phenotype-dependent differences in drug responses

Fig. 4

Capsaicin evokes a robust response in neurospheres but not adherent GL261 cells. a Pseudocolored images represent intracellular calcium levels in adherent (AC) or neurosphere (NS) GL261 cells under basal conditions and after exposure to 100 μM capsaicin (200X magnification). Pseudocolor scale bars depict the fura-2 signal ratio, with warmer colors indicating increased intracellular calcium concentrations. b Mean percentage of AC (n = 6) or NS (n = 9) GL261 cells that respond to 100 μM capsaicin. Bars indicate standard error of the mean. The difference between groups was significant (*) at a threshold of p < 0.05 (p = 0.0016, Student’s t-test)

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