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Table 3 Predictive factors on overall survival after liver resection

From: Outcome after resection of Adrenocortical Carcinoma liver metastases: a retrospective study

  Univariate analysis Multivariate analysis
  n median survival [mo] HR 95% CI p-value HR 95% CI p-value
Sex
 female 30 76.1 1      
 male 13 58.9 1.066 0.444 - 2.563 0.886    
Age at first liver resection (yr)
 ≤ 50 13 93.3 1      
 > 50 30 41.6 2.225 0.830 - 5.964 0.112    
Occurence of liver metastases
 secondary 30 89.3 1      
 simultaneous 13 23.3 1.485 0.673 - 3.278 0.327    
Major liver resection
 no 30 57.8 1      
 yes 11 93.3 0.580 0.226 - 1.488 0.257    
Number of liver metastases
 1 26 89.3 1    1   
 > 1 7 35.5 2.620 1.008 - 6.808 0.048 2.455 0.888 - 6.786 0.083
Pathologic margin
 R0 30 58.9       
 R1 8 93.3 1.037 0.372 - 2.889 0.945    
 Rx 5 92.3 1.127 0.401 - 3.167 0.821    
Side of primary tumour
 right 26 76.1 1      
 left 17 89.3 0.772 0.349 - 1.707 0.522    
Size of primary tumour (cm)
 ≤ 10 16 92.3 1      
 > 10 24 41.6 2.059 0.855 - 4.954 0.107    
Secreting primary tumour
 no 15 90.3 1      
 yes 21 42.6 1.624 0.665 - 3.962 0.287    
Chemotherapy after liver resection
 no 35 90.3 1    1   
 yes 8 17.3 12.176 3.765 - 39.373 < 0.001 3.453 0.774 - 15.410 0.104
Mitotane after liver resection
 no 22 90.3 1      
 yes 21 57.8 1.010 0.446 - 2.288 0.981    
Time to liver metastases [mo]
 > 12 25 90.3 1    1   
 ≤ 12 18 23.3 1.983 0.916 - 4.292 0.082 2.876 0.770 - 10.7431 0.116