Table 3 Predictive factors on overall survival after liver resection
From: Outcome after resection of Adrenocortical Carcinoma liver metastases: a retrospective study
Univariate analysis | Multivariate analysis | |||||||
|---|---|---|---|---|---|---|---|---|
n | median survival [mo] | HR | 95% CI | p-value | HR | 95% CI | p-value | |
Sex | ||||||||
female | 30 | 76.1 | 1 | |||||
male | 13 | 58.9 | 1.066 | 0.444 - 2.563 | 0.886 | |||
Age at first liver resection (yr) | ||||||||
≤ 50 | 13 | 93.3 | 1 | |||||
> 50 | 30 | 41.6 | 2.225 | 0.830 - 5.964 | 0.112 | |||
Occurence of liver metastases | ||||||||
secondary | 30 | 89.3 | 1 | |||||
simultaneous | 13 | 23.3 | 1.485 | 0.673 - 3.278 | 0.327 | |||
Major liver resection | ||||||||
no | 30 | 57.8 | 1 | |||||
yes | 11 | 93.3 | 0.580 | 0.226 - 1.488 | 0.257 | |||
Number of liver metastases | ||||||||
1 | 26 | 89.3 | 1 | 1 | ||||
> 1 | 7 | 35.5 | 2.620 | 1.008 - 6.808 | 0.048 | 2.455 | 0.888 - 6.786 | 0.083 |
Pathologic margin | ||||||||
R0 | 30 | 58.9 | ||||||
R1 | 8 | 93.3 | 1.037 | 0.372 - 2.889 | 0.945 | |||
Rx | 5 | 92.3 | 1.127 | 0.401 - 3.167 | 0.821 | |||
Side of primary tumour | ||||||||
right | 26 | 76.1 | 1 | |||||
left | 17 | 89.3 | 0.772 | 0.349 - 1.707 | 0.522 | |||
Size of primary tumour (cm) | ||||||||
≤ 10 | 16 | 92.3 | 1 | |||||
> 10 | 24 | 41.6 | 2.059 | 0.855 - 4.954 | 0.107 | |||
Secreting primary tumour | ||||||||
no | 15 | 90.3 | 1 | |||||
yes | 21 | 42.6 | 1.624 | 0.665 - 3.962 | 0.287 | |||
Chemotherapy after liver resection | ||||||||
no | 35 | 90.3 | 1 | 1 | ||||
yes | 8 | 17.3 | 12.176 | 3.765 - 39.373 | < 0.001 | 3.453 | 0.774 - 15.410 | 0.104 |
Mitotane after liver resection | ||||||||
no | 22 | 90.3 | 1 | |||||
yes | 21 | 57.8 | 1.010 | 0.446 - 2.288 | 0.981 | |||
Time to liver metastases [mo] | ||||||||
> 12 | 25 | 90.3 | 1 | 1 | ||||
≤ 12 | 18 | 23.3 | 1.983 | 0.916 - 4.292 | 0.082 | 2.876 | 0.770 - 10.7431 | 0.116 |