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Table 1 Basic patients’ characteristics

From: Outcome after resection of Adrenocortical Carcinoma liver metastases: a retrospective study

  overall Liver resection no Liver resection p-value
  n (%) n (%) n (%)
Patiens
overall 77   43   34   
female 56 (72.7%) 30 (69.8%) 26 (76.5%) 0.512
Mean age at first diagnosis [y] 49.5   45.5   54.5   0.016
Mean age at diagnosis of liver metastases [y] 49.8   46.0   54.7   0.017
Primary tumour
Localisation
 right gland 38 (49.4%) 26 (60.5%) 12 (35.3%) 0.061
 left gland 38 (49.4%) 17 (39.5%) 21 (61.8%)
 both glands 1 (1.3%) 0 (0.0%) 1 (2.9%)
Diameter
 > 10 cm 52 (67.5%) 24 (55.8%) 28 (82.4%) < 0.001
10 cm 17 (22.1%) 16 (37.2%) 1 (2.9%)
 unknown 5 (6.5%) 0 (0.0%) 5 (14.7%)
Hormon status at presentation
 functional 38 (49.4%) 21 (48.8%) 17 (50.0%) < 0.001
 non-functional 21 (27.3%) 15 (34.9%) 6 (17.6%)
 unknown 11 (14.3%) 0 (0.0%) 11 (32.4%)
Liver metastases
Simultaneous liver metastases 33 (42.9%) 13 (30.2%) 20 (58.8%) 0.012
Secondary liver metastases 44 (57.1%) 30 (69.8%) 14 (41.2%)
 Time between first diagnosis and liver metastases [m] 43.9   60.5   8.4   0.002
Number
 1 35 (45.5%) 26 (60.5%) 9 (26.5%) < 0.001
 2-5 12 (15.6%) 7 (16.3%) 5 (14.7%)
 > 5 20 (26.0%) 0 (0.0%) 20 (58.8%)
 unknown 10 (13.0%) 10 (23.3%) 0 (0.0%)
Systemic therapies after diagnosis of liver metastases
Mitotane 43 (55.8%) 21 (48.8%) 22 (64.7%) 0.164
Chemotherapy 24 (31.2%) 8 (18.6%) 16 (47.1%) 0.007