Table 1 Basic patients’ characteristics
From: Outcome after resection of Adrenocortical Carcinoma liver metastases: a retrospective study
overall | Liver resection | no Liver resection | p-value | ||||
|---|---|---|---|---|---|---|---|
n | (%) | n | (%) | n | (%) | ||
Patiens | |||||||
overall | 77 | 43 | 34 | ||||
female | 56 | (72.7%) | 30 | (69.8%) | 26 | (76.5%) | 0.512 |
Mean age at first diagnosis [y] | 49.5 | 45.5 | 54.5 | 0.016 | |||
Mean age at diagnosis of liver metastases [y] | 49.8 | 46.0 | 54.7 | 0.017 | |||
Primary tumour | |||||||
Localisation | |||||||
right gland | 38 | (49.4%) | 26 | (60.5%) | 12 | (35.3%) | 0.061 |
left gland | 38 | (49.4%) | 17 | (39.5%) | 21 | (61.8%) | |
both glands | 1 | (1.3%) | 0 | (0.0%) | 1 | (2.9%) | |
Diameter | |||||||
> 10 cm | 52 | (67.5%) | 24 | (55.8%) | 28 | (82.4%) | < 0.001 |
≦ 10 cm | 17 | (22.1%) | 16 | (37.2%) | 1 | (2.9%) | |
unknown | 5 | (6.5%) | 0 | (0.0%) | 5 | (14.7%) | |
Hormon status at presentation | |||||||
functional | 38 | (49.4%) | 21 | (48.8%) | 17 | (50.0%) | < 0.001 |
non-functional | 21 | (27.3%) | 15 | (34.9%) | 6 | (17.6%) | |
unknown | 11 | (14.3%) | 0 | (0.0%) | 11 | (32.4%) | |
Liver metastases | |||||||
Simultaneous liver metastases | 33 | (42.9%) | 13 | (30.2%) | 20 | (58.8%) | 0.012 |
Secondary liver metastases | 44 | (57.1%) | 30 | (69.8%) | 14 | (41.2%) | |
Time between first diagnosis and liver metastases [m] | 43.9 | 60.5 | 8.4 | 0.002 | |||
Number | |||||||
1 | 35 | (45.5%) | 26 | (60.5%) | 9 | (26.5%) | < 0.001 |
2-5 | 12 | (15.6%) | 7 | (16.3%) | 5 | (14.7%) | |
> 5 | 20 | (26.0%) | 0 | (0.0%) | 20 | (58.8%) | |
unknown | 10 | (13.0%) | 10 | (23.3%) | 0 | (0.0%) | |
Systemic therapies after diagnosis of liver metastases | |||||||
Mitotane | 43 | (55.8%) | 21 | (48.8%) | 22 | (64.7%) | 0.164 |
Chemotherapy | 24 | (31.2%) | 8 | (18.6%) | 16 | (47.1%) | 0.007 |