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Fig. 10 | BMC Cancer

Fig. 10

From: A type I combi-targeting approach for the design of molecules with enhanced potency against BRCA1/2 mutant- and O6-methylguanine-DNA methyltransferase (mgmt)- expressing tumour cells

Fig. 10

Subcellular distribution of ANI, EG22 and ZSM02 after a 2 h exposure. Following drug treatment, cells were washed with PBS, a drop of DAPI (NucBlue® Live ReadyProbes® Reagent, ThermoFicher Scientific) was added and 3-D images were taken with the appropriate filter. Nuclear localization of the drugs was confirmed by DAPI counterstaining

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BMC Cancer

ISSN: 1471-2407

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