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Table 2 Circulating calcium levels in control subjects and breast cancer cases expressing inactivating CaSR mutants

From: Association of calcium sensing receptor polymorphisms at rs1801725 with circulating calcium in breast cancer patients

Disease Status

Control subjects

Breast cancer cases

 

n

Median Calciuma

Rangeb

n

Median calcium

Range

p-Valuec

 

384

9.09 ± 0.54

8.76–9.45

199

9.29 ± 0.40

9.02–9.52

<0.001

Race

African Americans

Caucasians

 

All Samples

171

9.28 ± 0.45

9.02–9.54

412

9.11 ± 0.55

8.80–9.46

<0.001

CONTROL

113

9.26 ± 0.47

9.00–9.53

271

9.02 ± 0.55

8.67–9.37

<0.001

BC Cases

58

9.30 ± 0.39

9.03–9.60

141

9.29 ± 0.40

9.02–9.50

0.51

  1. amean circulating calcium ±1SD from multiple measurements over variable time periods. bthe lower and upper quartiles of circulating calcium levels for each group. cSignificance of the difference in circulating calcium between controls and breast cancer cases or between African American and Caucasian control subjects or BC cases. The p-values were calculated using the Wilcoxon rank sum test from the median with interquartile ranges for each group