Table 4 Adjusted HRs for overall survival stratified by LC and LWR changes in cohort 2 (N = 106)
Clinicopathological features | LC Model | LWR Model | ||
|---|---|---|---|---|
Adjusted HR(95% CI) | P value | Adjusted HR (95% CI) | P value | |
Gender (female vs. male) | 0.859(0.496 ~ 1.486) | 0.586 | 0.847(0.492 ~ 1.460) | 0.551 |
Age | 1.006(0.985 ~ 1.028) | 0.565 | 0.999(0.979 ~ 1.020) | 0.921 |
Primary tumor site | 0.787(0.618 ~ 1.003) | 0.053 | 0.751(0.590 ~ 0.955) | 0.019 |
Tumor stage (IV vs. III) | 2.813(1.076 ~ 7.356) | 0.035 | 1.971(0.738 ~ 5.263) | 0.176 |
Family history (Yes vs. No) | 1.405(0.846 ~ 2.333) | 0.189 | 1.424 (0.862 ~ 2.351) | 0.167 |
Smoke history (Yes vs. No) | 0.897(0.491 ~ 1.639) | 0.724 | 0.716(0.390 ~ 1.314) | 0.280 |
Nutrient (Abnormal vs. Normal) | 0.987(0.591 ~ 1.649) | 0.961 | 0.983(0.597 ~ 1.617) | 0.945 |
ECOG | 1.614(1.140 ~ 2.283) | 0.007 | 1.850(1.291 ~ 2.650) | 0.001 |
Concomitant disease (Yes vs. No) | 1.165(0.714 ~ 1.899) | 0.542 | 1.278(0.785 ~ 2.082) | 0.324 |
LC (Increased vs. Decreased) | 0.673(0.419 ~ 1.081) | 0.101 | -- | -- |
LWR(Increased vs. Decreased) | -- | -- | 0.396(0.243 ~ 0.668) | 0.001 |