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Table 2 Comparison of the clinical characteristics between duodenal and jejunal/ileal NENs

From: Clinicopathological features and prognostic validity of WHO grading classification of SI-NENs

 

Chinese Patients

White patients

Black patients

Asian/Pacific Islander patients

Duodenum

Jejunum/ileum

P

Duodenum

Jejunum/ileum

P

Duodenum

Jejunum/ileum

P

Duodenum

Jejunum/ileum

P

Age, years

  

0.452

  

<0.001

  

<0.001

  

0.157

 Mean

54.7

53.3

 

63.3

60.7

 

62.7

57.2

 

62.5

59.2

 

 95%CI

52.9–56.6

50.1–56.50

 

62.6–64.0

60.2–61.1

 

61.7–63.8

56.1–58.3

 

60.0–65.0

55.6–62.8

Sex

  

0.041

  

0.914

  

0.559

  

0.527

 Male

113 (53.3%)

44 (67.7%)

 

763 (49.5%)

1631 (49.7%)

 

264 (46.4%)

187 (44.5%)

 

60 (48.8%)

26 (54.2%)

 

 Female

99 (46.7%)

21 (32.3%)

 

778 (50.5%)

1652 (50.3%)

 

305 (53.6%)

233 (55.5%)

 

63 (51.2%)

22 (45.8%)

Tumor size, cm

  

<0.001

  

<0.001

  

<0.001

  

0.001

 Median

2.0

3.0

 

1.0

1.9

 

1.0

1.9

 

1.0

1.5

 

Tumor gradea

191b

58c

0.227

  

-

  

-

  

-

 Grade 1

74 (38.7%)

17 (29.3%)

          

 Grade 2

57 (29.8%)

24 (41.4%)

         

 Grade 3

60 (31.4%)

17 (29.3%)

         

Tumor differentiation

  

-

658d

1647e

<0.001

223f

202g

0.149

47h

21i

0.232

 Well differentiated

   

497 (75.5%)

1268 (77.0%)

 

171 (76.7%)

169 (83.7%)

 

38 (80.9%)

14 (66.7%)

 

 Moderately differentiated

   

98 (14.9%)

321 (19.5%)

 

43 (19.3%)

25 (12.4%)

 

4 (8.5%)

5 (23.8%)

 Poorly or undifferentiated

   

63 (9.6%)

58 (3.5%)

 

9 (4.0%)

8 (4.0%)

 

5 (10.6%)

2 (9.5%)

T status

169b

53c

<0.001

890d

2559e

<0.001

300f

339g

<0.001

72h

38i

<0.001

 T1

34 (20.1%)

3 (5.7%)

 

497 (55.8%)

283 (11.1%)

 

165 (55.0%)

33 (9.7%)

 

34 (47.2%)

5 (13.2%)

 

 T2

67 (39.6%)

9 (17.0%)

 

279 (31.3%)

584 (22.8%)

 

109 (36.3%)

102 (30.1%)

 

27 (37.5%)

9 (23.7%)

 T3

56 (33.1%)

35 (66.0%)

 

62 (7.0%)

1044 (40.8%)

 

17 (5.7%)

128 (37.8%)

 

6 (8.3%)

14 (36.8%)

 T4

12 (7.1%)

6 (11.3%)

 

52 (5.8%)

648 (25.3%)

 

9 (3.0%)

76 (22.4%)

 

5 (6.9%)

10 (26.3%)

N status

188b

59c

<0.001

1332d

3146e

<0.001

479f

401g

<0.001

109h

47i

<0.001

 N0

127 (67.6%)

22 (37.3%)

 

1154 (86.6%)

930 (29.6%)

 

421 (87.9%)

142 (35.4%)

 

94 (86.2%)

15 (31.9%)

 

 N1

61 (32.4%)

37 (62.7%)

 

178 (13.4%)

2216 (70.4%)

 

58 (12.1%)

259 (64.6%)

 

15 (13.8%)

32 (68.1%)

M status

212b

65c

0.090

1308d

2672e

<0.001

458f

353g

<0.001

119h

48i

<0.001

 M0

171 (80.7%)

46 (70.8%)

 

1217 (93.0%)

1908 (71.4%)

 

434 (94.8%)

267 (75.6%)

 

112 (94.1%)

36 (75.0%)

 

 M1

41 (19.3%)

19 (29.2%)

 

91 (7.0%)

764 (28.6%)

 

24 (5.2%)

86 (24.4%)

 

7 (5.9%)

12 (25.0%)

Tumor stage

183b

58c

<0.001

817d

2548e

<0.001

273f

330g

<0.001

76h

47i

<0.001

 I

30 (16.4%)

2 (3.4%)

 

407 (49.8%)

132 (5.2%)

 

134 (49.1%)

16 (4.8%)

 

34 (44.7%)

5 (10.6%)

 

 II

75 (41.0%)

13 (22.4%)

 

190 (23.3%)

305 (12.0%)

 

75 (27.5%)

53 (16.1%)

 

20 (26.3%)

7 (14.9%)

 III

37 (20.2%)

24 (41.4%)

 

129 (15.8%)

1347 (52.9%)

 

40 (14.7%)

175 (53.0%)

 

15 (19.7%)

23 (48.9%)

 IV

41 (22.4%)

19 (32.8%)

 

91 (11.1%)

764 (30.0%)

 

24 (8.8%)

86 (26.1%)

 

7 (9.2%)

12 (25.5%)

  1. aTumor grade was based on WHO 2010 classification criteria (grade 1, 2 and 3) in Chinese patients. b,cThe number available in Chinese SI-NENs patients with 212 patients of duodenal NENs and 65 patients of jejunal/ileal NENs in total. d,eThe number available in SEER database with 1541 white patients of duodenal NENs and 3283 white patients of jejunal/ileal NENs in total. f,gThe number available in SEER database with 569 black patients of duodenal NENs and 420 black patients of jejunal/ileal NENs in total. h, iThe number available in SEER database with 123 Asian/Pacific Islander patients of duodenal NENs and 48 Asian/Pacific Islander patients of jejunal/ileal NENs
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BMC Cancer

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