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Table 4 Multivariate analysis including ERCC1 expression in all cancers, ERG-negative and ERG-positive subset

From: Increased ERCC1 expression is linked to chromosomal aberrations and adverse tumor biology in prostate cancer

Tumor subset Scenario n analyzable p value  
Preoperative PSA-Level pT Stage cT Stage Gleason grade prostatectomy Gleason grade biopsy pN Stage R Stage ERCC1-Expression
All cancers 1 5644 0.0009 <0.0001 - <0.0001 - <0.0001 0.0008 0.0746
2 9193 <0.0001 <0.0001 - <0.0001 - - <0.0001 0.0052
3 9062 <0.0001 - <0.0001 <0.0001 - - - 0.0045
4 8926 <0.0001 - <0.0001 - <0.0001 - - <0.0001
ERG-negative subset 1 2829 <0.0001 <0.0001 - <0.0001 - 0.0001 0.0846 0.1110
2 4471 <0.0001 <0.0001 - <0.0001 - - 0.0002 0.0184
3 4432 <0.0001 - <0.0001 <0.0001 - - - 0.0526
4 4368 <0.0001 - <0.0001 - <0.0001 - - <0.0001
ERG-positive subset 1 2242 0.0057 <0.0001 - <0.0001 - 0.0763 0.0092 0.0626
2 3584 <0.0001 <0.0001 - <0.0001 - - <0.0001 0.0613
3 3506 <0.0001 - <0.0001 <0.0001 - - - 0.0746
4 3451 <0.0001 - <0.0001 - <0.0001 - - 0.0009