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Table 4 Multivariate analysis including ERCC1 expression in all cancers, ERG-negative and ERG-positive subset

From: Increased ERCC1 expression is linked to chromosomal aberrations and adverse tumor biology in prostate cancer

Tumor subset

Scenario

n analyzable

p value

 

Preoperative PSA-Level

pT Stage

cT Stage

Gleason grade prostatectomy

Gleason grade biopsy

pN Stage

R Stage

ERCC1-Expression

All cancers

1

5644

0.0009

<0.0001

-

<0.0001

-

<0.0001

0.0008

0.0746

2

9193

<0.0001

<0.0001

-

<0.0001

-

-

<0.0001

0.0052

3

9062

<0.0001

-

<0.0001

<0.0001

-

-

-

0.0045

4

8926

<0.0001

-

<0.0001

-

<0.0001

-

-

<0.0001

ERG-negative subset

1

2829

<0.0001

<0.0001

-

<0.0001

-

0.0001

0.0846

0.1110

2

4471

<0.0001

<0.0001

-

<0.0001

-

-

0.0002

0.0184

3

4432

<0.0001

-

<0.0001

<0.0001

-

-

-

0.0526

4

4368

<0.0001

-

<0.0001

-

<0.0001

-

-

<0.0001

ERG-positive subset

1

2242

0.0057

<0.0001

-

<0.0001

-

0.0763

0.0092

0.0626

2

3584

<0.0001

<0.0001

-

<0.0001

-

-

<0.0001

0.0613

3

3506

<0.0001

-

<0.0001

<0.0001

-

-

-

0.0746

4

3451

<0.0001

-

<0.0001

-

<0.0001

-

-

0.0009