Psychosocial and behavioral impact of breast cancer risk assessed by testing for common risk variants: protocol of a prospective study

Table 1 Measures selected for study and corresponding questionnaires

Measure	Q1 Baseline	Q2 Receivers	Q3 Receivers	Q3 Decliners
Predictor Variables
1. Demographic characteristics	√
2. Protection motivation	√
3. Perceived severity of breast cancer	√
4. Response efficacy	√
5. Response cost	√
6. Self-efficacy	√
7. Uncertainty avoidance	√
Confounding Variable
8. Stressful life events	√		√	√
Predictor and Outcome Variables
9. Perceived breast cancer risk	√	√	√
10. Knowledge of familial breast cancer and polygenic risk	√	√	√
11. Breast cancer anxiety	√	√	√	√
Outcome Variables
12. General anxiety and depression	√	√	√	√
13. Concordance with screening guidelines	√		√	√
14. Intention to take up and actual uptake of preventative strategies	√	√	√	√
15. Regret over testing decision		√	√	√
16. Recall and interpretation of results		√	√
17. Test-related distress, positive experiences and uncertainty		√	√
18. Reasons for declining results				√

ISSN: 1471-2407