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Table 3 Cox proportional hazard ratio estimates for death in pancreatic cancer subjects

From: Expression of the scaffold connector enhancer of kinase suppressor of Ras 1 (CNKSR1) is correlated with clinical outcome in pancreatic cancer

Hazard Ratio Estimates for CNK Negative Status
Unadjusted model Hazard Ratio 95% Confidence Limits p value
 CNK 0–1 1.611 1.057–2.457 0.027
Adjusted model Hazard Ratio 95% Confidence Limits  
 CNK 0–1 2.146 1.341–3.434 0.0014
 No Resection 3.783 2.089–6.852 <0.0001
 Distant Metastasis (M0 vs M1) 2.834 1.584–5.069 0.0004
 Regional Lymph Nodes (N0 vs N1) 1.893 1.206–2.972 0.0055
 65+ Years at Diagnosis 1.550 1.018–2.359 0.041
 Male 1.233 0.821–1.851 0.26
 Moderately Differentiated 1.014 0.580–1.772 0.96
 Poorly Differentiated 0.830 0.508–1.356 0.45
 Non-Palliative Radiationa 0.674 0.370–1.231 0.19
 White 0.611 0.288–1.298 0.20
 Asian 0.583 0.268–1.266 0.17
  1. aReferent groups for respective variables were subjects with high CNKSR1 expression, those with resections, localized or regional stage cancer at diagnosis, females, cases less than 65 years of age, with localized or regional stage radiation therapy, Black or Hispanic race/ethnicity