Prognostic value of total tumor volume in patients with nasopharyngeal carcinoma treated with intensity-modulated radiotherapy

Table 3 Multivariate analyses of prognostic factors in 316 patients with stage III-IVb

Endpoint	Variable	HR	95% CI	P-value
FFS	TTV	3.362	1.677–6.738	0.001
OS	Sex	1.735	0.906–3.321	0.096
	Additional boost	1.860	0.947–3.654	0.072
	Chemotherapy	2.384	1.109–5.126	0.026
	N stage^a	1.551	0.994–2.421	0.053
	TTV	4.364	2.125–8.964	<0.001
DMFS	TTV	2.923	1.323–6.459	0.008
LRRFS	TTV	2.464	0.951–6.383	0.063

^aAccording to the 7th edition of the American Joint Commission on Cancer staging system; HR hazard ratio, CI confidence interval, FFS failure free survival, OS overall survival, DMFS distant metastasis-free survival, LRRFS loco-regional relapse free survival, TTV total tumor volume, RT radiotherapy

ISSN: 1471-2407