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Table 2 Multivariate analyses of prognostic factors in all 455 patients

From: Prognostic value of total tumor volume in patients with nasopharyngeal carcinoma treated with intensity-modulated radiotherapy

Endpoint

Variable

HR

95% CI

P-value

FFS

TTV

4.523

2.482–8.241

<0.001

N stagea

1.567

1.027–2.391

0.037

OS

Sex

1.661

0.915–3.013

0.095

Chemotherapy

1.882

0.986–3.592

0.055

T stagea

1.763

1.054–2.951

0.031

N stagea

1.920

1.254–2.939

0.003

TTV

3.231

1.776–5.878

<0.001

DMFS

N stagea

1.764

1.064–2.925

0.028

TTV

3.749

1.877–7.489

<0.001

LRRFS

TTV

3.810

1.679–8.645

0.001

  1. aAccording to the 7th edition of the American Joint Commission on Cancer staging system; HR hazard ratio, CI confidence interval, FFS failure free survival, OS overall survival, DMFS distant metastasis-free survival, LRRFS loco-regional relapse free survival, TTV total tumor volume