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Table 2 Multivariate analyses of prognostic factors in all 455 patients

From: Prognostic value of total tumor volume in patients with nasopharyngeal carcinoma treated with intensity-modulated radiotherapy

Endpoint Variable HR 95% CI P-value
FFS TTV 4.523 2.482–8.241 <0.001
N stagea 1.567 1.027–2.391 0.037
OS Sex 1.661 0.915–3.013 0.095
Chemotherapy 1.882 0.986–3.592 0.055
T stagea 1.763 1.054–2.951 0.031
N stagea 1.920 1.254–2.939 0.003
TTV 3.231 1.776–5.878 <0.001
DMFS N stagea 1.764 1.064–2.925 0.028
TTV 3.749 1.877–7.489 <0.001
LRRFS TTV 3.810 1.679–8.645 0.001
  1. aAccording to the 7th edition of the American Joint Commission on Cancer staging system; HR hazard ratio, CI confidence interval, FFS failure free survival, OS overall survival, DMFS distant metastasis-free survival, LRRFS loco-regional relapse free survival, TTV total tumor volume