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Table 4 Summary of univariate and multivariate Cox regression analysis of overall survival duration in all NPC patients (n = 50)

From: JMJD2A promotes the Warburg effect and nasopharyngeal carcinoma progression by transactivating LDHA expression

Clinicopathological parameters Univariate analysis Multivariate analysis
HR 95% CI P-value HR 95% CI P-value
JMJD2A(High/Low) 2.539 1.233–5.228 0.011* 2.652 1.245–5.650 0.011*
LDHA(High/Low) 3.652 1.721–7.749 0.001* 3.433 1.560–7.556 0.002*
Gender (Female/Male) 2.324 0.954–5.662 0.063    
Age(years)(≥50/<50) 0.681 0.341–1.357 0.681    
Histological type(UDC/DNKC) 0.614 0.308–1.224 0.166    
T classification(T3 + T4/T1 + T2) 1.351 0.679–2.687 0.391    
N classification (N2 + N3/N0 + N1) 2.941 1.160–7.455 0.023*    
M classification (M1/M0) 2.349 1.107–4.984 0.026*    
Clinical stage (III + IV/I + II) 2.291 1.096–4.788 0.028*    
  1. HR hazard ratio, 95% CI 95% confidence interval, *indicates P < 0.05