Skip to main content

Table 2 Survival using univariate-multivariate analysis according to risk factors

From: Real-life clinical practice results with vinflunine in patients with relapsed platinum-treated metastatic urothelial carcinoma: an Italian multicenter study (MOVIE-GOIRC 01–2014)

      Multivariate
  n (%) Median (months) [95% CI] Log rank HR [95% CI] P-value
Hemoglobin
  ≥ 10 191 (88) 8.5 [6.8–9.6] 0.067    
  < 10 26 (12) 4.8 [3.2–8.6]   1.45 0.93–2.25 0.097
ECOG PS
 0 101 (47) 9.8 [5.8–18.2] <0.001    
  ≥ 1 116 (53) 5.6 [4.6–8.4]   1.68 1.26–2.25 <0.001
Number of metastatic sites
 1 127 (58) 9.5 [4.6–17.3] <0.001    
  ≥ 2 90 (42) 5.8 [2.6–10.9]   1.48 1.08–2.03 0.014
Liver metastases
 No 170 (78) 8.6 [3.9–16.0] 0.004    
 Yes 47 (22) 6.8 [3.1–8.5]   1.51 1.02–2.24 0.04
Visceral Involvement
 No 102 (47) 8.8 [3.9–15.0] 0.136    
 Yes 115 (53) 7.5 [3.0–11.9]   1.03 0.75–1.42 0.839
Time from prior chemotherapy
  ≥ 3 m 141 (65) 8.0 [5.9–8.9] 0.187    
  < 3 m 76 (35) 8.1 [3.6–13.8]   1.19 0.88–1.62 0.264
  1. CI confidence interval, ECOG PS Eastern Cooperative Oncology Group Performance Status, HR hazard ratio