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Table 2 Hazard ratios for risk of biochemical recurrence by UGT2B15, UGT2B17, UGT2B28 measures

From: UDP-glucuronosyltransferases and biochemical recurrence in prostate cancer progression

  UGT2B15 UGT2B17 UGT2B28
Predictor HR (95% CI) p-value HR (95% CI) p-value HR (95% CI) p-value
% Positive
 Crude 1.98 (0.90-1.07) 0.70 1.11 (0.98-1.25) 0.09 1.02 (0.92-1.13) 0.70
 Adjusteda 1.02 (0.93-1.12) 0.72 1.10 (0.98-1.25) 0.11 1.08 (0.96-1.21) 0.21
H-score
 Crude 0.99 (0.91-1.07) 0.80 1.05 (0.97-1.13) 0.21 1.00 (0.94-1.06) 0.89
 Adjusteda 1.03 (0.94-1.12) 0.57 1.03 (0.96-1.11) 0.42 1.04 (0.97-1.11) 0.26
  1. aAdjusted for PSA, age, pathological Gleason score, race, year of surgery, positive margins, extracapsular extension, and seminal vesicle invasion
  2. All biomarkers are modeled per 10-unit increase