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Table 2 Hazard ratios for risk of biochemical recurrence by UGT2B15, UGT2B17, UGT2B28 measures

From: UDP-glucuronosyltransferases and biochemical recurrence in prostate cancer progression

 

UGT2B15

UGT2B17

UGT2B28

Predictor

HR (95% CI)

p-value

HR (95% CI)

p-value

HR (95% CI)

p-value

% Positive

 Crude

1.98 (0.90-1.07)

0.70

1.11 (0.98-1.25)

0.09

1.02 (0.92-1.13)

0.70

 Adjusteda

1.02 (0.93-1.12)

0.72

1.10 (0.98-1.25)

0.11

1.08 (0.96-1.21)

0.21

H-score

 Crude

0.99 (0.91-1.07)

0.80

1.05 (0.97-1.13)

0.21

1.00 (0.94-1.06)

0.89

 Adjusteda

1.03 (0.94-1.12)

0.57

1.03 (0.96-1.11)

0.42

1.04 (0.97-1.11)

0.26

  1. aAdjusted for PSA, age, pathological Gleason score, race, year of surgery, positive margins, extracapsular extension, and seminal vesicle invasion
  2. All biomarkers are modeled per 10-unit increase