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Table 3 Categorization of differentially expressed proteins according to Gene Ontology Molecular Function

From: Proteomic characterization of paired non-malignant and malignant African-American prostate epithelial cell lines distinguishes them by structural proteins

Gene Ontology Molecular Function Annotation (Number of Differentially Expressed Proteins)
Binding Proteins (21)
• eukaryotic translation initiation factor 4B • RNA-binding protein EWS • high mobility group protein HMG-I/HMG-Y
• double-stranded RNA-specific adenosine deaminase • plasminogen activator inhibitor 1 RNA-binding protein • non-histone chromosomal protein HMG-17
• alpha-actinin-1 • nucleolar RNA helicase 2 • 60S ribosomal protein L35
• hepatoma-derived growth factor • gamma-interferon-inducible protein 16 • 60S ribosomal protein L10
• PDZ and LIM domain protein 1 • non-histone chromosomal protein HMG-14 • high mobility group protein HMGI-C
• caveolin-1 • calpastatin • beta-catenin
• 60S ribosomal protein L6 • filamin-A • myosin heavy chain-9
Catalytic Activity Proteins (21)
• serotransferrin • aminopeptidase N • calpastatin
• double-stranded RNA-specific adenosine deaminase • putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 • type I cytoskeletal high mobility group protein HMG-I/HMG-Y
• cytosolic acyl coenzyme A thioester hydrolase • hydroxyacyl-coenzyme A dehydrogenase • S-formylglutathione hydrolase
• phosphoenolpyruvate carboxykinase • cytochrome c oxidase subunit 5A • S-methyl-5′-thioadenosine phosphorylase
• creatine kinase U-type • 60S ribosomal protein L35 • caveolin-1
• myosin heavy chain-9 • adenosylhomocysteinase • nucleolar RNA helicase 2
• high mobility group protein HMGI-C • phosphoserine aminotransferase • RNA-binding protein EWS
Structural Molecule Activity (13)
• filamin-A • 60S ribosomal protein L10 • 60S ribosomal protein L35
• Type I cytoskeletal keratin 19 • type II cytoskeletal keratin 8 • PDZ and LIM domain protein 1
• Myosin heavy chain-9 • 60S ribosomal protein L6 • 40S ribosomal protein S11
• alpha-actinin-1 • vimentin • lamin-B1
• caveolin-1